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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LSM2 All Species: 50.3
Human Site: Y69 Identified Species: 85.13
UniProt: Q9Y333 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y333 NP_067000.1 95 10835 Y69 I R G S V V R Y V Q L P A D E
Chimpanzee Pan troglodytes XP_518362 176 19302 Y150 I R G S V V R Y V Q L P A D E
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9QXA5 137 15058 L69 R G S T I K Y L R I P D E I I
Rat Rattus norvegicus NP_001004073 131 14761 Y105 I R G S V V R Y V Q L P A D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520666 188 20509 Y162 I R G S V V R Y V Q L P A D E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_571571 95 10804 Y69 I R G S V V R Y V Q L P A D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648570 95 10719 Y69 I R G S V V R Y V Q L P G D E
Honey Bee Apis mellifera XP_001120188 95 10702 Y69 I R G S V V R Y V Q L P G D E
Nematode Worm Caenorhab. elegans NP_506348 97 11009 Y69 I R G S V V R Y V Q L P S D Q
Sea Urchin Strong. purpuratus XP_792582 95 10721 Y69 I R G S V V R Y V Q L P A D E
Poplar Tree Populus trichocarpa XP_002304049 93 10689 Y69 I R G S V V R Y V Q L P P E G
Maize Zea mays NP_001152698 93 10705 Y69 I R G S V V R Y V L L P Q D G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_563682 93 10676 Y69 I R G S V V R Y V Q L P K D G
Baker's Yeast Sacchar. cerevisiae P38203 95 11144 Y69 I R G S T V R Y V Y L N K N M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.9 N.A. N.A. N.A. 22.6 72.5 N.A. 50.5 N.A. N.A. 98.9 N.A. 91.5 92.6 82.4 90.5
Protein Similarity: 100 53.9 N.A. N.A. N.A. 39.4 72.5 N.A. 50.5 N.A. N.A. 98.9 N.A. 95.7 95.7 93.8 93.6
P-Site Identity: 100 100 N.A. N.A. N.A. 0 100 N.A. 100 N.A. N.A. 100 N.A. 93.3 93.3 86.6 100
P-Site Similarity: 100 100 N.A. N.A. N.A. 13.3 100 N.A. 100 N.A. N.A. 100 N.A. 93.3 93.3 100 100
Percent
Protein Identity: 70.5 69.4 N.A. 71.5 63.1 N.A.
Protein Similarity: 81 80 N.A. 82.1 81 N.A.
P-Site Identity: 80 80 N.A. 86.6 60 N.A.
P-Site Similarity: 86.6 80 N.A. 86.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 43 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 79 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 58 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 93 0 0 0 0 0 0 0 0 0 15 0 22 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 93 0 0 0 8 0 0 0 0 8 0 0 0 8 8 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 0 15 0 0 % K
% Leu: 0 0 0 0 0 0 0 8 0 8 93 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 8 86 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 79 0 0 8 0 8 % Q
% Arg: 8 93 0 0 0 0 93 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 8 93 0 0 0 0 0 0 0 0 8 0 0 % S
% Thr: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 86 93 0 0 93 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 93 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _