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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLK5
All Species:
16.97
Human Site:
S195
Identified Species:
53.33
UniProt:
Q9Y337
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y337
NP_001070959.1
293
32019
S195
S
G
W
G
T
T
K
S
P
Q
V
H
F
P
K
Chimpanzee
Pan troglodytes
XP_001159973
406
44182
S308
S
G
W
G
T
T
K
S
P
Q
V
R
F
P
K
Rhesus Macaque
Macaca mulatta
XP_001116247
291
31726
P194
G
W
G
T
T
R
S
P
Q
V
H
F
P
K
V
Dog
Lupus familis
XP_541469
294
31843
S196
S
G
W
G
T
T
N
S
P
N
V
Q
F
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYN3
276
30735
S178
S
G
W
G
T
T
S
S
P
Q
L
R
L
P
H
Rat
Rattus norvegicus
O88780
260
28491
P163
G
W
G
T
V
T
S
P
Q
E
N
F
P
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90629
248
26604
S151
S
G
W
G
N
T
L
S
N
G
Y
N
Y
P
E
Frog
Xenopus laevis
P70059
244
26061
S147
S
G
W
G
N
T
L
S
S
G
T
N
Y
P
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.6
93.8
77.2
N.A.
42.3
41.6
N.A.
N.A.
40.2
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
70.9
97.2
89.4
N.A.
58.7
58.7
N.A.
N.A.
54.6
56.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
80
N.A.
66.6
6.6
N.A.
N.A.
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
80
N.A.
73.3
13.3
N.A.
N.A.
66.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% D
% Glu:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
25
38
0
0
% F
% Gly:
25
75
25
75
0
0
0
0
0
25
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
13
0
0
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
25
0
0
0
0
0
0
13
38
% K
% Leu:
0
0
0
0
0
0
25
0
0
0
13
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
13
0
13
13
13
25
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
25
50
0
0
0
25
75
0
% P
% Gln:
0
0
0
0
0
0
0
0
25
38
0
13
0
0
0
% Q
% Arg:
0
0
0
0
0
13
0
0
0
0
0
25
0
0
0
% R
% Ser:
75
0
0
0
0
0
38
75
13
0
0
0
0
0
0
% S
% Thr:
0
0
0
25
63
88
0
0
0
0
13
0
0
0
13
% T
% Val:
0
0
0
0
13
0
0
0
0
13
38
0
0
0
13
% V
% Trp:
0
25
75
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
13
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _