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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A5
All Species:
18.18
Human Site:
S135
Identified Species:
33.33
UniProt:
Q9Y345
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y345
NP_004202.2
797
87360
S135
P
E
G
D
A
N
V
S
V
G
K
G
T
L
E
Chimpanzee
Pan troglodytes
XP_521869
797
87347
S135
P
E
G
D
A
N
V
S
V
G
K
G
T
L
E
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
N24
D
G
E
D
C
Q
E
N
G
V
L
Q
K
V
V
Dog
Lupus familis
XP_854917
904
97792
S242
P
E
G
D
A
A
A
S
V
G
K
G
T
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q761V0
799
87843
S137
P
E
E
D
A
N
V
S
V
G
K
G
T
L
E
Rat
Rattus norvegicus
P58295
799
87890
S137
P
E
E
D
E
N
V
S
V
A
K
G
T
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505647
364
39960
Chicken
Gallus gallus
XP_420906
854
94085
A193
T
D
G
D
A
N
A
A
L
G
K
S
T
L
E
Frog
Xenopus laevis
A7Y2X0
790
87434
E128
I
V
P
L
Q
S
A
E
G
D
T
N
Q
G
F
Zebra Danio
Brachydanio rerio
NP_001009557
786
87171
T128
N
N
S
T
G
D
W
T
S
M
S
Q
T
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51905
622
69307
T16
F
A
G
A
A
A
T
T
G
R
S
N
P
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03614
615
69247
D8
M
Q
L
V
P
T
D
D
P
D
E
K
I
G
R
Sea Urchin
Strong. purpuratus
XP_001179122
659
73488
L53
N
V
W
R
F
P
Y
L
A
Y
E
N
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
36.1
79.6
N.A.
94.2
94.2
N.A.
41.5
76.6
77.6
68.8
N.A.
36
N.A.
33.8
40.9
Protein Similarity:
100
99.5
52.9
81.9
N.A.
95.3
95.2
N.A.
42.7
82.1
84.6
77.6
N.A.
52.5
N.A.
50.5
54.2
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
80
N.A.
0
60
0
6.6
N.A.
13.3
N.A.
0
0
P-Site Similarity:
100
100
20
86.6
N.A.
93.3
80
N.A.
0
80
6.6
20
N.A.
20
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
47
16
24
8
8
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
54
0
8
8
8
0
16
0
0
0
0
0
% D
% Glu:
0
39
24
0
8
0
8
8
0
0
16
0
0
0
47
% E
% Phe:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
39
0
8
0
0
0
24
39
0
39
8
24
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
47
8
8
0
0
% K
% Leu:
0
0
8
8
0
0
0
8
8
0
8
0
0
47
0
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
16
8
0
0
0
39
0
8
0
0
0
24
0
0
0
% N
% Pro:
39
0
8
0
8
8
0
0
8
0
0
0
8
0
8
% P
% Gln:
0
8
0
0
8
8
0
0
0
0
0
16
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% R
% Ser:
0
0
8
0
0
8
0
39
8
0
16
8
0
0
0
% S
% Thr:
8
0
0
8
0
8
8
16
0
0
8
0
54
8
0
% T
% Val:
0
16
0
8
0
0
31
0
39
8
0
0
0
8
8
% V
% Trp:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _