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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC6A5
All Species:
16.06
Human Site:
S91
Identified Species:
29.44
UniProt:
Q9Y345
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y345
NP_004202.2
797
87360
S91
S
P
R
A
Q
A
A
S
A
A
L
R
D
L
R
Chimpanzee
Pan troglodytes
XP_521869
797
87347
S91
S
P
R
A
Q
A
A
S
A
A
L
R
D
L
R
Rhesus Macaque
Macaca mulatta
Q9MYX0
630
70239
Dog
Lupus familis
XP_854917
904
97792
S198
T
G
A
P
T
F
Q
S
P
D
A
R
A
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q761V0
799
87843
S93
S
P
R
A
Q
A
T
S
A
A
L
R
D
L
S
Rat
Rattus norvegicus
P58295
799
87890
S93
S
P
Q
A
Q
A
T
S
A
A
L
R
D
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505647
364
39960
Chicken
Gallus gallus
XP_420906
854
94085
S149
S
T
P
V
Q
A
N
S
M
L
R
R
E
S
A
Frog
Xenopus laevis
A7Y2X0
790
87434
T84
G
G
S
C
K
M
T
T
P
G
H
S
N
F
V
Zebra Danio
Brachydanio rerio
NP_001009557
786
87171
N84
G
P
T
F
A
G
V
N
S
A
V
R
K
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51905
622
69307
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03614
615
69247
Sea Urchin
Strong. purpuratus
XP_001179122
659
73488
A9
G
K
A
I
E
D
G
A
V
E
V
L
E
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
36.1
79.6
N.A.
94.2
94.2
N.A.
41.5
76.6
77.6
68.8
N.A.
36
N.A.
33.8
40.9
Protein Similarity:
100
99.5
52.9
81.9
N.A.
95.3
95.2
N.A.
42.7
82.1
84.6
77.6
N.A.
52.5
N.A.
50.5
54.2
P-Site Identity:
100
100
0
13.3
N.A.
86.6
80
N.A.
0
33.3
0
20
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
0
20
N.A.
86.6
86.6
N.A.
0
40
20
40
N.A.
0
N.A.
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
31
8
39
16
8
31
39
8
0
8
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
8
0
0
31
8
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
8
0
0
16
8
8
% E
% Phe:
0
0
0
8
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
24
16
0
0
0
8
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
31
8
0
31
0
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
8
% N
% Pro:
0
39
8
8
0
0
0
0
16
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
39
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
24
0
0
0
0
0
0
0
8
54
0
8
16
% R
% Ser:
39
0
8
0
0
0
0
47
8
0
0
8
0
8
24
% S
% Thr:
8
8
8
0
8
0
24
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
8
0
8
0
16
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _