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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3GLB1
All Species:
36.06
Human Site:
S218
Identified Species:
79.33
UniProt:
Q9Y371
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y371
NP_057093.1
365
40796
S218
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Chimpanzee
Pan troglodytes
XP_520303
400
44342
S244
L
L
L
E
G
I
S
S
T
H
V
N
H
L
R
Rhesus Macaque
Macaca mulatta
XP_001109639
365
40748
S218
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Dog
Lupus familis
XP_855325
448
50224
S302
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JK48
365
40837
S218
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Rat
Rattus norvegicus
Q6AYE2
365
40769
S218
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508524
364
40538
S216
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Chicken
Gallus gallus
Q5ZIR1
366
40777
S218
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Frog
Xenopus laevis
Q6GM14
376
42749
K209
D
R
L
E
R
E
R
K
E
R
E
Q
R
E
A
Zebra Danio
Brachydanio rerio
NP_001017617
360
40174
S215
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191773
357
39709
L211
Y
E
I
T
T
L
L
L
E
G
I
T
S
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.5
99.7
74.7
N.A.
95.8
94.7
N.A.
87.6
86.8
20.4
75.3
N.A.
N.A.
N.A.
N.A.
55.3
Protein Similarity:
100
75.5
99.7
78.1
N.A.
96.9
96.7
N.A.
92.8
92
33.7
84.6
N.A.
N.A.
N.A.
N.A.
71.7
P-Site Identity:
100
86.6
100
100
N.A.
100
100
N.A.
100
100
13.3
100
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
100
100
13.3
100
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
73
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
91
0
10
0
0
19
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
82
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
82
0
73
82
0
10
% H
% Ile:
0
0
10
0
0
82
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
82
82
91
0
0
10
10
10
0
0
0
0
0
82
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
10
0
0
10
0
10
0
0
10
0
0
10
0
82
% R
% Ser:
0
0
0
0
0
0
82
82
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
10
10
0
0
0
82
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _