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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAB39 All Species: 38.79
Human Site: Y223 Identified Species: 77.58
UniProt: Q9Y376 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y376 NP_001124321.1 341 39869 Y223 K L L H S E N Y V T K R Q S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112762 341 39881 Y223 K L L H S E N Y V T K R Q S L
Dog Lupus familis XP_534599 341 39852 Y223 K L L H S E N Y V T K R Q S L
Cat Felis silvestris
Mouse Mus musculus Q06138 341 39823 Y223 K L L H S E N Y V T K R Q S L
Rat Rattus norvegicus NP_001011917 337 39073 Y222 K L L Q S E N Y V T K R Q S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001085141 341 39759 Y223 K L L H S E N Y V T K R Q S L
Zebra Danio Brachydanio rerio NP_001002145 341 39773 Y223 K L L H S E N Y V T K R Q S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91891 339 39367 N222 Q R L L N S E N Y V T R R Q S
Honey Bee Apis mellifera XP_393376 338 39432 Y222 R L L N S E N Y V T R R Q S L
Nematode Worm Caenorhab. elegans O18211 338 39413 Y226 A L T N S E N Y V T R R Q S L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M0M4 343 39632 N227 S K L L E S T N Y I T R R Q A
Baker's Yeast Sacchar. cerevisiae P32464 399 45835 Y244 K L M A H G S Y V T K R Q S T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 99.4 N.A. 98.8 79.1 N.A. N.A. N.A. 98.2 92.9 N.A. 70.3 72.4 60.1 N.A.
Protein Similarity: 100 N.A. 99.7 99.7 N.A. 99.1 89.1 N.A. N.A. N.A. 99.4 97 N.A. 85.9 85.6 77.1 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 93.3 N.A. N.A. N.A. 100 100 N.A. 13.3 80 73.3 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 93.3 N.A. N.A. N.A. 100 100 N.A. 33.3 100 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 42.8 28.8 N.A.
Protein Similarity: N.A. N.A. N.A. 67.6 49.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 75 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 50 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 67 9 0 0 0 0 0 0 0 0 67 0 0 0 0 % K
% Leu: 0 84 84 17 0 0 0 0 0 0 0 0 0 0 75 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 9 0 75 17 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 9 0 0 0 0 0 0 0 0 84 17 0 % Q
% Arg: 9 9 0 0 0 0 0 0 0 0 17 100 17 0 0 % R
% Ser: 9 0 0 0 75 17 9 0 0 0 0 0 0 84 9 % S
% Thr: 0 0 9 0 0 0 9 0 0 84 17 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 0 84 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 84 17 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _