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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2J1 All Species: 13.03
Human Site: S261 Identified Species: 17.92
UniProt: Q9Y385 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y385 NP_057105.2 318 35199 S261 Q R R A Q Q Q S Q R R L S T S
Chimpanzee Pan troglodytes XP_518636 318 35166 S261 Q R R A Q Q Q S Q R R L S T S
Rhesus Macaque Macaca mulatta XP_001096217 318 35120 S261 Q R R A Q Q Q S Q R R S S T S
Dog Lupus familis XP_532230 305 33567 Q249 R R A Q Q Q S Q R R S S T S P
Cat Felis silvestris
Mouse Mus musculus Q9JJZ4 318 34971 S261 Q R R A Q Q Q S Q R R P S T S
Rat Rattus norvegicus NP_001100112 249 27861 G193 K A E V N S S G K T I A E S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513572 437 47819 Q381 R R A Q Q H S Q R G A S T S P
Chicken Gallus gallus NP_990094 317 34755 A261 L S P R Q R R A Q Q H S Q R W
Frog Xenopus laevis NP_001091402 302 33372 Q246 S P R Q R R A Q Q R R T P A S
Zebra Danio Brachydanio rerio NP_999932 314 34258 Q258 R Q R R S Q N Q S P R S P V F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393288 265 29807 Q209 I S E N Q L R Q R G V E S I N
Nematode Worm Caenorhab. elegans NP_001040755 314 35297 Q258 V Q P I R D P Q P L V F Q H H
Sea Urchin Strong. purpuratus XP_792623 370 40402 Q260 H N P P T P Q Q P S D V G N A
Poplar Tree Populus trichocarpa XP_002312335 310 34437 K254 A S R E V P A K C S S D Q L L
Maize Zea mays NP_001150768 309 33945 I253 E A X R R E S I P R V P S S L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LSP7 309 34304 A253 A V E V V V K A S V S G E Q R
Baker's Yeast Sacchar. cerevisiae P33296 250 28365 K193 F T K A A K E K V I S L E E I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.8 89.9 N.A. 92.4 71.3 N.A. 61.5 76.7 73.2 66 N.A. N.A. 48.1 44.6 46.2
Protein Similarity: 100 100 98.1 91.1 N.A. 94.6 74.5 N.A. 64.9 82.6 80.8 76.7 N.A. N.A. 61.3 61.9 58.1
P-Site Identity: 100 100 93.3 26.6 N.A. 93.3 0 N.A. 13.3 13.3 33.3 20 N.A. N.A. 13.3 0 6.6
P-Site Similarity: 100 100 93.3 53.3 N.A. 93.3 20 N.A. 40 40 46.6 33.3 N.A. N.A. 33.3 13.3 20
Percent
Protein Identity: 38.9 34.9 N.A. 36.1 28.6 N.A.
Protein Similarity: 55.3 54 N.A. 54.4 45.9 N.A.
P-Site Identity: 6.6 13.3 N.A. 0 13.3 N.A.
P-Site Similarity: 6.6 40 N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 12 30 6 0 12 12 0 0 6 6 0 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 6 0 0 0 0 6 6 0 0 6 % D
% Glu: 6 0 18 6 0 6 6 0 0 0 0 6 18 6 0 % E
% Phe: 6 0 0 0 0 0 0 0 0 0 0 6 0 0 6 % F
% Gly: 0 0 0 0 0 0 0 6 0 12 0 6 6 0 0 % G
% His: 6 0 0 0 0 6 0 0 0 0 6 0 0 6 6 % H
% Ile: 6 0 0 6 0 0 0 6 0 6 6 0 0 6 6 % I
% Lys: 6 0 6 0 0 6 6 12 6 0 0 0 0 0 0 % K
% Leu: 6 0 0 0 0 6 0 0 0 6 0 18 0 6 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 6 0 6 6 0 6 0 0 0 0 0 0 6 6 % N
% Pro: 0 6 18 6 0 12 6 0 18 6 0 12 12 0 12 % P
% Gln: 24 12 0 18 48 36 30 42 36 6 0 0 18 6 0 % Q
% Arg: 18 36 42 18 18 12 12 0 18 42 36 0 0 6 6 % R
% Ser: 6 18 0 0 6 6 24 24 12 12 24 30 36 24 30 % S
% Thr: 0 6 0 0 6 0 0 0 0 6 0 6 12 24 0 % T
% Val: 6 6 0 12 12 6 0 0 6 6 18 6 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _