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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS7
All Species:
10.3
Human Site:
S151
Identified Species:
18.89
UniProt:
Q9Y394
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y394
NP_057113.1
339
38299
S151
R
S
L
C
M
D
T
S
L
D
V
Y
R
K
L
Chimpanzee
Pan troglodytes
XP_001167105
453
49615
S265
R
S
L
C
M
D
T
S
L
D
V
Y
R
K
L
Rhesus Macaque
Macaca mulatta
XP_001095790
339
38156
S151
R
S
L
C
M
D
T
S
L
D
V
Y
R
K
L
Dog
Lupus familis
XP_537465
437
48705
N249
R
S
L
C
V
D
T
N
L
D
V
F
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXR1
338
38149
N151
R
S
L
V
L
E
T
N
L
D
V
F
K
E
L
Rat
Rattus norvegicus
Q5RJY4
325
35324
Y135
E
I
L
Q
C
F
G
Y
V
D
I
L
I
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6PUF4
287
31460
V102
S
P
S
E
P
D
R
V
V
Q
F
A
V
Q
N
Frog
Xenopus laevis
Q0IH28
323
35135
R119
E
I
L
H
L
A
G
R
V
D
I
L
I
N
N
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
H120
E
I
L
K
R
H
G
H
V
D
V
L
I
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
Q134
R
V
L
A
V
Y
N
Q
V
D
I
L
I
N
N
Honey Bee
Apis mellifera
XP_395330
305
34248
H115
D
I
L
D
I
N
K
H
E
L
V
F
N
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785686
344
38401
K148
T
I
V
D
R
Y
G
K
I
D
I
L
I
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_186983
328
35770
A134
D
Y
L
V
H
N
A
A
F
E
R
P
K
S
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
96.1
65.9
N.A.
79.3
33
N.A.
N.A.
26.5
31.5
28.6
N.A.
30.6
36.5
N.A.
44.4
Protein Similarity:
100
74.6
97.6
71.8
N.A.
87.3
52.5
N.A.
N.A.
44.2
52.2
48
N.A.
51.6
53.6
N.A.
64.8
P-Site Identity:
100
100
100
66.6
N.A.
53.3
13.3
N.A.
N.A.
6.6
13.3
20
N.A.
20
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
N.A.
20
33.3
33.3
N.A.
40
40
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
8
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
31
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
16
0
39
0
0
0
77
0
0
0
0
0
% D
% Glu:
24
0
0
8
0
8
0
0
8
8
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
8
24
0
0
0
% F
% Gly:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
8
8
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
39
0
0
8
0
0
0
8
0
31
0
39
0
16
% I
% Lys:
0
0
0
8
0
0
8
8
0
0
0
0
24
24
8
% K
% Leu:
0
0
85
0
16
0
0
0
39
8
0
39
0
0
39
% L
% Met:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
16
8
16
0
0
0
0
8
39
39
% N
% Pro:
0
8
0
0
8
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
8
0
8
0
0
0
8
0
% Q
% Arg:
47
0
0
0
16
0
8
8
0
0
8
0
24
0
0
% R
% Ser:
8
39
8
0
0
0
0
24
0
0
0
0
0
16
0
% S
% Thr:
8
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% T
% Val:
0
8
8
16
16
0
0
8
39
0
54
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
16
0
8
0
0
0
24
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _