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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS7
All Species:
16.97
Human Site:
S190
Identified Species:
31.11
UniProt:
Q9Y394
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y394
NP_057113.1
339
38299
S190
G
K
I
V
T
V
N
S
I
L
G
I
I
S
V
Chimpanzee
Pan troglodytes
XP_001167105
453
49615
S304
G
K
I
V
T
V
N
S
I
L
G
I
I
S
V
Rhesus Macaque
Macaca mulatta
XP_001095790
339
38156
S190
G
K
I
V
T
V
N
S
I
L
G
I
I
S
A
Dog
Lupus familis
XP_537465
437
48705
S288
G
K
I
V
T
V
N
S
L
L
G
I
I
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXR1
338
38149
S190
G
K
I
V
T
V
N
S
I
A
G
I
A
S
V
Rat
Rattus norvegicus
Q5RJY4
325
35324
A176
G
P
V
A
L
T
K
A
L
L
P
S
M
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6PUF4
287
31460
L139
D
V
E
H
T
R
W
L
M
Q
V
N
F
F
S
Frog
Xenopus laevis
Q0IH28
323
35135
A160
G
P
V
A
L
T
K
A
L
L
P
S
M
I
K
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
A161
G
P
V
A
L
T
Q
A
I
L
P
S
M
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
A175
G
S
V
A
L
T
K
A
L
L
P
S
M
V
K
Honey Bee
Apis mellifera
XP_395330
305
34248
D157
S
V
D
K
E
L
F
D
L
N
V
F
S
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785686
344
38401
E196
V
A
L
P
Y
M
L
E
N
N
Y
G
Q
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_186983
328
35770
G178
H
M
L
K
Q
G
G
G
H
F
V
V
I
S
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
96.1
65.9
N.A.
79.3
33
N.A.
N.A.
26.5
31.5
28.6
N.A.
30.6
36.5
N.A.
44.4
Protein Similarity:
100
74.6
97.6
71.8
N.A.
87.3
52.5
N.A.
N.A.
44.2
52.2
48
N.A.
51.6
53.6
N.A.
64.8
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
13.3
N.A.
N.A.
6.6
13.3
20
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
40
N.A.
N.A.
13.3
40
40
N.A.
40
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
31
0
0
0
31
0
8
0
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
0
8
8
8
0
% F
% Gly:
70
0
0
0
0
8
8
8
0
0
39
8
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
39
0
0
0
0
0
39
0
0
39
39
16
16
% I
% Lys:
0
39
0
16
0
0
24
0
0
0
0
0
0
0
16
% K
% Leu:
0
0
16
0
31
8
8
8
39
62
0
0
0
0
0
% L
% Met:
0
8
0
0
0
8
0
0
8
0
0
0
31
0
0
% M
% Asn:
0
0
0
0
0
0
39
0
8
16
0
8
0
0
0
% N
% Pro:
0
24
0
8
0
0
0
0
0
0
31
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
8
0
0
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
0
0
0
39
0
0
0
31
8
47
16
% S
% Thr:
0
0
0
0
47
31
0
0
0
0
0
0
0
8
0
% T
% Val:
8
16
31
39
0
39
0
0
0
0
24
8
0
24
24
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _