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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS7
All Species:
18.48
Human Site:
T115
Identified Species:
33.89
UniProt:
Q9Y394
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y394
NP_057113.1
339
38299
T115
L
P
L
D
L
T
D
T
G
S
H
E
A
A
T
Chimpanzee
Pan troglodytes
XP_001167105
453
49615
T229
L
P
L
D
L
T
D
T
G
S
H
E
A
A
T
Rhesus Macaque
Macaca mulatta
XP_001095790
339
38156
T115
L
P
L
D
L
T
D
T
G
S
H
E
A
A
T
Dog
Lupus familis
XP_537465
437
48705
R213
L
P
L
D
L
T
D
R
S
S
H
E
A
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXR1
338
38149
T115
L
P
L
D
L
T
D
T
S
S
H
E
A
A
T
Rat
Rattus norvegicus
Q5RJY4
325
35324
S99
F
T
R
E
L
A
D
S
S
S
S
Q
G
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6PUF4
287
31460
L71
T
A
R
R
E
A
V
L
Q
E
V
M
K
K
C
Frog
Xenopus laevis
Q0IH28
323
35135
L85
Q
E
L
N
N
M
R
L
K
S
T
Q
L
H
K
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
Y86
E
E
L
G
N
K
T
Y
G
K
T
K
T
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
L100
V
K
K
D
L
L
A
L
D
V
D
P
A
Y
P
Honey Bee
Apis mellifera
XP_395330
305
34248
T81
I
L
S
S
R
T
E
T
K
L
E
K
V
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785686
344
38401
P115
R
G
N
C
V
R
F
P
E
V
R
E
E
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_186983
328
35770
L103
V
K
V
L
P
L
D
L
A
S
G
E
E
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
96.1
65.9
N.A.
79.3
33
N.A.
N.A.
26.5
31.5
28.6
N.A.
30.6
36.5
N.A.
44.4
Protein Similarity:
100
74.6
97.6
71.8
N.A.
87.3
52.5
N.A.
N.A.
44.2
52.2
48
N.A.
51.6
53.6
N.A.
64.8
P-Site Identity:
100
100
100
86.6
N.A.
93.3
26.6
N.A.
N.A.
0
13.3
20
N.A.
20
20
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
46.6
N.A.
N.A.
0
26.6
26.6
N.A.
26.6
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
16
8
0
8
0
0
0
47
39
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
47
0
0
54
0
8
0
8
0
0
0
0
% D
% Glu:
8
16
0
8
8
0
8
0
8
8
8
54
16
0
0
% E
% Phe:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
0
0
0
31
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
39
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
16
8
0
0
8
0
0
16
8
0
16
8
16
8
% K
% Leu:
39
8
54
8
54
16
0
31
0
8
0
0
8
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
8
16
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
39
0
0
8
0
0
8
0
0
0
8
0
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
8
0
0
16
0
8
0
% Q
% Arg:
8
0
16
8
8
8
8
8
0
0
8
0
0
0
0
% R
% Ser:
0
0
8
8
0
0
0
8
24
62
8
0
0
8
0
% S
% Thr:
8
8
0
0
0
47
8
39
0
0
16
0
8
0
62
% T
% Val:
16
0
8
0
8
0
8
0
0
16
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _