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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS7
All Species:
20.91
Human Site:
T253
Identified Species:
38.33
UniProt:
Q9Y394
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y394
NP_057113.1
339
38299
T253
L
A
G
E
V
T
K
T
I
G
N
N
G
D
Q
Chimpanzee
Pan troglodytes
XP_001167105
453
49615
T367
L
T
G
E
V
T
K
T
I
G
N
N
G
D
Q
Rhesus Macaque
Macaca mulatta
XP_001095790
339
38156
T253
L
A
G
E
V
T
K
T
I
A
N
N
G
D
Q
Dog
Lupus familis
XP_537465
437
48705
S351
L
T
E
E
V
T
K
S
V
G
I
D
T
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXR1
338
38149
S253
F
T
E
E
V
T
K
S
M
R
N
N
I
D
Q
Rat
Rattus norvegicus
Q5RJY4
325
35324
Y239
V
T
V
I
S
P
G
Y
I
H
T
N
L
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6PUF4
287
31460
T202
S
S
L
R
H
E
L
T
M
Q
K
R
N
V
S
Frog
Xenopus laevis
Q0IH28
323
35135
Y223
V
T
V
V
N
P
G
Y
I
K
T
N
L
S
L
Zebra Danio
Brachydanio rerio
Q566S6
309
33329
Y224
V
S
V
L
S
P
G
Y
V
R
T
N
M
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y140
326
35725
Y238
V
S
C
V
S
P
G
Y
I
R
T
Q
L
S
L
Honey Bee
Apis mellifera
XP_395330
305
34248
C220
N
I
S
I
T
I
V
C
P
G
P
V
E
T
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785686
344
38401
E259
P
V
V
S
N
I
V
E
N
A
L
R
E
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_186983
328
35770
T241
W
N
G
T
G
T
S
T
S
E
D
S
K
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
96.1
65.9
N.A.
79.3
33
N.A.
N.A.
26.5
31.5
28.6
N.A.
30.6
36.5
N.A.
44.4
Protein Similarity:
100
74.6
97.6
71.8
N.A.
87.3
52.5
N.A.
N.A.
44.2
52.2
48
N.A.
51.6
53.6
N.A.
64.8
P-Site Identity:
100
93.3
93.3
46.6
N.A.
53.3
13.3
N.A.
N.A.
6.6
13.3
6.6
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
66.6
20
N.A.
N.A.
20
20
26.6
N.A.
20
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
0
0
0
16
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
8
0
39
0
% D
% Glu:
0
0
16
39
0
8
0
8
0
8
0
0
16
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
31
0
8
0
31
0
0
31
0
0
24
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
16
0
16
0
0
47
0
8
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
39
0
0
8
8
0
8
0
0
% K
% Leu:
31
0
8
8
0
0
8
0
0
0
8
0
24
0
16
% L
% Met:
0
0
0
0
0
0
0
0
16
0
0
0
8
0
0
% M
% Asn:
8
8
0
0
16
0
0
0
8
0
31
54
8
0
8
% N
% Pro:
8
0
0
0
0
31
0
0
8
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
39
% Q
% Arg:
0
0
0
8
0
0
0
0
0
24
0
16
0
0
0
% R
% Ser:
8
24
8
8
24
0
8
16
8
0
0
8
0
39
8
% S
% Thr:
0
39
0
8
8
47
0
39
0
0
31
0
8
8
0
% T
% Val:
31
8
31
16
39
0
16
0
16
0
0
8
0
16
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _