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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED5
All Species:
34.85
Human Site:
S91
Identified Species:
69.7
UniProt:
Q9Y3A6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3A6
NP_057124.2
229
26005
S91
L
V
F
E
Q
R
K
S
D
G
V
H
T
V
E
Chimpanzee
Pan troglodytes
XP_001154650
229
26004
S91
L
V
F
E
Q
R
K
S
D
G
V
H
T
V
E
Rhesus Macaque
Macaca mulatta
XP_001103770
227
25115
A89
L
V
S
E
S
R
K
A
D
G
V
H
T
V
E
Dog
Lupus familis
XP_537072
472
52286
S334
L
V
F
E
Q
R
K
S
D
G
V
H
T
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXE7
229
26153
S91
L
V
F
E
Q
R
K
S
D
G
V
H
T
I
E
Rat
Rattus norvegicus
Q6AXN3
229
26117
S91
L
V
F
E
Q
R
K
S
D
G
V
H
T
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508464
269
30032
S131
L
I
S
E
Q
R
K
S
D
G
V
H
T
V
D
Chicken
Gallus gallus
NP_001007957
226
25656
S88
L
V
F
D
E
R
K
S
D
G
V
H
T
V
E
Frog
Xenopus laevis
NP_001090383
224
25760
S86
L
L
S
E
E
R
Q
S
D
G
V
H
S
V
E
Zebra Danio
Brachydanio rerio
NP_956697
225
25592
S88
I
A
S
D
Y
R
K
S
D
G
V
H
T
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502288
234
26569
D82
K
Q
D
Q
L
K
V
D
G
S
H
R
I
E
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12450
207
23497
E79
D
G
S
V
I
V
T
E
R
Q
K
K
H
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
55.4
46.8
N.A.
89.9
90.3
N.A.
62
83.4
68.5
66.8
N.A.
N.A.
N.A.
40.5
N.A.
Protein Similarity:
100
100
72
47.8
N.A.
94.7
95.1
N.A.
71.3
91.2
82
79.9
N.A.
N.A.
N.A.
61.1
N.A.
P-Site Identity:
100
100
80
100
N.A.
93.3
100
N.A.
80
86.6
66.6
66.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
93.3
100
93.3
80
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
17
0
0
0
9
84
0
0
0
0
0
17
% D
% Glu:
0
0
0
67
17
0
0
9
0
0
0
0
0
9
75
% E
% Phe:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
9
84
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
84
9
0
0
% H
% Ile:
9
9
0
0
9
0
0
0
0
0
0
0
9
9
0
% I
% Lys:
9
0
0
0
0
9
75
0
0
0
9
9
0
0
0
% K
% Leu:
75
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
9
50
0
9
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
84
0
0
9
0
0
9
0
0
0
% R
% Ser:
0
0
42
0
9
0
0
75
0
9
0
0
9
9
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
75
0
0
% T
% Val:
0
59
0
9
0
9
9
0
0
0
84
0
0
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _