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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED7
All Species:
28.18
Human Site:
T166
Identified Species:
47.69
UniProt:
Q9Y3B3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B3
NP_861974.1
224
25172
T166
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Chimpanzee
Pan troglodytes
XP_001147460
404
46120
T166
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Rhesus Macaque
Macaca mulatta
XP_001085143
224
25026
T166
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Dog
Lupus familis
XP_858610
226
25282
T168
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
Q162
L
K
T
V
I
D
S
Q
T
H
Y
R
L
R
E
Rat
Rattus norvegicus
Q6AY25
221
25492
Q162
L
K
T
V
I
D
S
Q
T
H
Y
R
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
T274
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Chicken
Gallus gallus
XP_413948
205
23206
N147
V
T
I
H
E
A
L
N
A
V
I
D
S
Q
T
Frog
Xenopus laevis
NP_001087434
219
25215
T161
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
T159
K
S
V
M
D
Y
Q
T
H
F
R
L
R
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393052
202
23290
S145
T
V
H
K
N
L
N
S
I
L
D
Y
Q
T
H
Nematode Worm
Caenorhab. elegans
O17528
203
22968
V146
L
S
S
A
L
M
S
V
K
H
E
Q
E
Y
M
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
Q154
L
K
A
V
V
N
F
Q
T
H
Y
R
L
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
K155
E
I
D
R
N
L
N
K
I
T
K
T
L
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.9
99.1
96.9
N.A.
62.9
62.9
N.A.
56.6
56.2
82.1
77.2
N.A.
N.A.
50.4
32.1
50.8
Protein Similarity:
100
54.7
99.1
97.3
N.A.
77.2
76.3
N.A.
60.2
69.1
87.5
87.5
N.A.
N.A.
66
49.5
68.7
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
100
0
100
93.3
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
6.6
6.6
N.A.
100
26.6
100
100
N.A.
N.A.
20
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
0
8
0
0
0
0
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
50
15
0
0
0
0
8
8
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
8
0
8
50
22
% E
% Phe:
0
0
0
0
0
0
8
0
0
50
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
8
0
0
0
0
50
29
0
0
0
0
8
% H
% Ile:
0
8
8
43
15
0
0
0
15
0
8
0
0
0
0
% I
% Lys:
50
22
0
8
0
0
0
8
8
0
8
0
0
0
0
% K
% Leu:
29
0
0
0
8
15
8
0
0
8
0
50
29
0
0
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
15
8
15
8
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
50
22
0
0
0
8
8
8
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
50
22
50
22
0
% R
% Ser:
0
58
8
0
0
0
22
8
0
0
0
0
8
0
0
% S
% Thr:
8
8
15
0
0
0
0
50
22
8
0
8
0
8
8
% T
% Val:
8
8
50
22
8
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
50
0
0
0
0
22
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _