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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED7
All Species:
23.94
Human Site:
T218
Identified Species:
40.51
UniProt:
Q9Y3B3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B3
NP_861974.1
224
25172
T218
F
F
S
D
K
R
T
T
T
T
R
V
G
S
_
Chimpanzee
Pan troglodytes
XP_001147460
404
46120
S218
L
C
N
V
A
E
H
S
N
T
T
E
G
P
T
Rhesus Macaque
Macaca mulatta
XP_001085143
224
25026
T218
F
F
S
D
K
R
T
T
T
T
R
V
G
S
_
Dog
Lupus familis
XP_858610
226
25282
T220
F
F
S
D
K
R
T
T
T
T
R
V
G
S
_
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
P214
S
F
F
T
E
K
R
P
V
N
R
A
V
H
S
Rat
Rattus norvegicus
Q6AY25
221
25492
P214
S
F
F
T
E
K
R
P
I
N
R
A
V
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
T326
F
F
S
D
K
R
T
T
T
T
R
V
G
S
_
Chicken
Gallus gallus
XP_413948
205
23206
P199
Q
P
Q
P
T
L
G
P
G
L
Q
P
P
Q
_
Frog
Xenopus laevis
NP_001087434
219
25215
T213
F
F
S
D
K
R
T
T
T
T
R
V
G
S
_
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
T211
F
F
S
D
R
K
T
T
T
T
R
M
G
S
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393052
202
23290
Nematode Worm
Caenorhab. elegans
O17528
203
22968
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
F207
V
L
L
I
Q
F
L
F
T
G
R
Q
K
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.9
99.1
96.9
N.A.
62.9
62.9
N.A.
56.6
56.2
82.1
77.2
N.A.
N.A.
50.4
32.1
50.8
Protein Similarity:
100
54.7
99.1
97.3
N.A.
77.2
76.3
N.A.
60.2
69.1
87.5
87.5
N.A.
N.A.
66
49.5
68.7
P-Site Identity:
100
13.3
100
100
N.A.
13.3
13.3
N.A.
100
0
100
78.5
N.A.
N.A.
0
0
0
P-Site Similarity:
100
26.6
100
100
N.A.
26.6
26.6
N.A.
100
7.1
100
100
N.A.
N.A.
0
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
15
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
43
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
15
8
0
0
0
0
0
8
0
0
0
% E
% Phe:
43
58
15
0
0
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
8
8
0
0
50
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
15
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
36
22
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
8
8
0
0
8
8
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
15
0
0
0
8
0
% N
% Pro:
0
8
0
8
0
0
0
22
0
0
0
8
8
8
0
% P
% Gln:
8
0
8
0
8
0
0
0
0
0
8
8
0
8
0
% Q
% Arg:
0
0
0
0
8
36
15
0
0
0
65
0
0
0
0
% R
% Ser:
15
0
43
0
0
0
0
8
0
0
0
0
0
43
15
% S
% Thr:
0
0
0
15
8
0
43
43
50
50
8
0
0
0
8
% T
% Val:
8
0
0
8
0
0
0
0
8
0
0
36
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% _