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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED7
All Species:
41.21
Human Site:
Y123
Identified Species:
69.74
UniProt:
Q9Y3B3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B3
NP_861974.1
224
25172
Y123
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
E
Chimpanzee
Pan troglodytes
XP_001147460
404
46120
Y123
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
E
Rhesus Macaque
Macaca mulatta
XP_001085143
224
25026
Y123
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
E
Dog
Lupus familis
XP_858610
226
25282
Y125
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
Y119
T
F
S
H
K
T
V
Y
F
D
F
Q
V
G
D
Rat
Rattus norvegicus
Q6AY25
221
25492
Y119
T
F
S
H
K
T
V
Y
F
D
F
Q
V
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
Y231
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
E
Chicken
Gallus gallus
XP_413948
205
23206
F104
F
S
N
E
F
S
T
F
S
H
K
T
V
Y
F
Frog
Xenopus laevis
NP_001087434
219
25215
Y118
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
D
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
Y116
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393052
202
23290
F102
K
A
C
F
S
N
E
F
S
T
F
S
H
K
L
Nematode Worm
Caenorhab. elegans
O17528
203
22968
A103
M
S
T
M
T
P
K
A
V
M
F
T
V
E
I
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
Y111
T
F
A
H
K
V
V
Y
F
D
F
M
A
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
T112
C
F
S
N
N
Y
G
T
A
L
K
K
V
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.9
99.1
96.9
N.A.
62.9
62.9
N.A.
56.6
56.2
82.1
77.2
N.A.
N.A.
50.4
32.1
50.8
Protein Similarity:
100
54.7
99.1
97.3
N.A.
77.2
76.3
N.A.
60.2
69.1
87.5
87.5
N.A.
N.A.
66
49.5
68.7
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
100
6.6
93.3
93.3
N.A.
N.A.
6.6
20
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
100
100
N.A.
N.A.
13.3
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
8
0
0
0
8
0
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
72
0
0
0
0
36
% D
% Glu:
0
0
0
8
0
0
8
0
0
0
0
0
0
15
36
% E
% Phe:
8
79
0
8
8
0
0
15
72
0
86
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
72
0
% G
% His:
0
0
0
72
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
8
0
0
0
72
0
8
0
0
0
15
8
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% L
% Met:
8
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
8
8
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
65
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
22
0
8
8
0
0
15
0
0
8
0
0
0
% S
% Thr:
72
0
58
0
8
65
8
8
0
8
0
15
0
0
0
% T
% Val:
0
0
0
0
0
8
72
0
8
0
0
0
86
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
72
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _