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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED7
All Species:
24.55
Human Site:
Y188
Identified Species:
41.54
UniProt:
Q9Y3B3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B3
NP_861974.1
224
25172
Y188
D
L
N
T
R
V
A
Y
W
S
V
G
E
A
L
Chimpanzee
Pan troglodytes
XP_001147460
404
46120
Y188
D
L
N
T
R
V
A
Y
W
H
S
V
D
T
S
Rhesus Macaque
Macaca mulatta
XP_001085143
224
25026
Y188
D
L
N
T
R
V
A
Y
W
S
V
G
E
A
L
Dog
Lupus familis
XP_858610
226
25282
Y190
D
L
N
T
R
V
A
Y
W
S
V
G
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
S184
E
D
L
N
S
R
V
S
Y
W
S
V
G
E
T
Rat
Rattus norvegicus
Q6AY25
221
25492
S184
E
D
L
N
S
R
V
S
Y
W
S
V
G
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
Y296
D
L
N
T
R
V
A
Y
W
S
V
G
E
A
I
Chicken
Gallus gallus
XP_413948
205
23206
D169
Q
D
R
S
R
A
E
D
L
N
G
R
V
S
Y
Frog
Xenopus laevis
NP_001087434
219
25215
Y183
D
L
N
S
R
V
A
Y
W
S
V
G
E
A
V
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
F181
D
L
N
S
R
V
A
F
W
S
V
G
E
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393052
202
23290
L167
G
R
K
R
A
E
D
L
N
T
R
V
L
L
W
Nematode Worm
Caenorhab. elegans
O17528
203
22968
N168
R
N
I
N
E
N
T
N
S
R
V
V
M
W
A
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
H176
E
R
L
N
K
R
V
H
L
W
S
L
G
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
T177
N
M
S
T
V
N
S
T
E
S
R
L
T
W
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.9
99.1
96.9
N.A.
62.9
62.9
N.A.
56.6
56.2
82.1
77.2
N.A.
N.A.
50.4
32.1
50.8
Protein Similarity:
100
54.7
99.1
97.3
N.A.
77.2
76.3
N.A.
60.2
69.1
87.5
87.5
N.A.
N.A.
66
49.5
68.7
P-Site Identity:
100
60
100
100
N.A.
0
0
N.A.
93.3
6.6
86.6
86.6
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
66.6
100
100
N.A.
13.3
13.3
N.A.
100
26.6
100
100
N.A.
N.A.
6.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
50
0
0
0
0
0
0
43
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
22
0
0
0
0
8
8
0
0
0
0
8
0
0
% D
% Glu:
22
0
0
0
8
8
8
0
8
0
0
0
43
22
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
8
43
22
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
50
22
0
0
0
0
8
15
0
0
15
8
8
36
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
50
29
0
15
0
8
8
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
15
8
8
58
22
0
0
0
8
15
8
0
0
0
% R
% Ser:
0
0
8
22
15
0
8
15
8
50
29
0
0
8
8
% S
% Thr:
0
0
0
43
0
0
8
8
0
8
0
0
8
8
15
% T
% Val:
0
0
0
0
8
50
22
0
0
0
50
36
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
50
22
0
0
0
15
8
% W
% Tyr:
0
0
0
0
0
0
0
43
15
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _