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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO2
All Species:
26.67
Human Site:
S193
Identified Species:
45.13
UniProt:
Q9Y3B8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B8
NP_056338.2
237
26833
S193
F
A
P
K
K
A
A
S
H
R
A
L
D
D
I
Chimpanzee
Pan troglodytes
XP_001150488
222
25256
S178
F
A
P
K
K
A
A
S
H
R
A
L
D
D
I
Rhesus Macaque
Macaca mulatta
XP_001087552
237
26863
S193
F
A
P
K
K
A
A
S
H
R
A
L
D
D
I
Dog
Lupus familis
XP_546513
121
14387
I88
L
D
D
I
S
E
S
I
K
E
L
Q
F
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8S4
237
26720
S193
F
A
P
K
K
A
A
S
H
R
A
L
D
D
I
Rat
Rattus norvegicus
Q5U1X1
237
26733
S193
F
A
P
K
K
A
A
S
H
R
A
L
D
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514027
350
39624
S194
F
A
Q
K
K
T
A
S
H
R
A
L
D
D
I
Chicken
Gallus gallus
XP_417900
233
26632
S189
F
A
P
K
K
A
A
S
H
R
A
L
D
D
I
Frog
Xenopus laevis
NP_001088822
186
21652
A153
H
P
V
E
Y
R
L
A
P
K
K
A
A
S
H
Zebra Danio
Brachydanio rerio
NP_957038
199
22942
I166
S
H
R
A
L
D
D
I
Q
E
S
I
K
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCI0
211
24279
I178
A
K
R
W
H
P
A
I
L
D
S
A
P
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780396
196
23147
E163
C
R
R
W
Y
R
E
E
Y
E
A
G
N
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131502
249
28052
Q213
W
Y
P
K
E
R
K
Q
T
P
R
K
Q
K
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVE0
222
24913
K189
W
F
P
I
E
R
R
K
A
P
A
K
K
N
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
99.1
49.7
N.A.
94
94.5
N.A.
60
83.9
68.3
68.7
N.A.
42.1
N.A.
N.A.
53.5
Protein Similarity:
100
93.6
99.1
49.7
N.A.
96.1
96.6
N.A.
62.8
89.4
73.8
75.9
N.A.
59.9
N.A.
N.A.
64.5
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
86.6
100
0
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
86.6
100
20
26.6
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
42.5
N.A.
40.5
N.A.
N.A.
Protein Similarity:
N.A.
59
N.A.
56.9
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
0
8
0
43
58
8
8
0
65
15
8
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
8
8
0
0
8
0
0
50
50
0
% D
% Glu:
0
0
0
8
15
8
8
8
0
22
0
0
0
8
0
% E
% Phe:
50
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
8
8
0
0
8
0
0
0
50
0
0
0
0
0
8
% H
% Ile:
0
0
0
15
0
0
0
22
0
0
0
8
0
0
50
% I
% Lys:
0
8
0
58
50
0
8
8
8
8
8
15
15
15
15
% K
% Leu:
8
0
0
0
8
0
8
0
8
0
8
50
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% N
% Pro:
0
8
58
0
0
8
0
0
8
15
0
0
8
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
8
0
0
8
8
8
0
% Q
% Arg:
0
8
22
0
0
29
8
0
0
50
8
0
0
0
8
% R
% Ser:
8
0
0
0
8
0
8
50
0
0
15
0
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
15
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
15
0
0
0
8
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _