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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO2
All Species:
22.73
Human Site:
S92
Identified Species:
38.46
UniProt:
Q9Y3B8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B8
NP_056338.2
237
26833
S92
Q
P
D
E
L
L
D
S
M
S
D
W
C
K
E
Chimpanzee
Pan troglodytes
XP_001150488
222
25256
E77
S
D
L
N
I
L
A
E
G
P
N
L
I
I
K
Rhesus Macaque
Macaca mulatta
XP_001087552
237
26863
S92
Q
P
D
E
L
L
D
S
M
S
D
W
C
K
E
Dog
Lupus familis
XP_546513
121
14387
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8S4
237
26720
S92
Q
P
D
E
L
L
D
S
M
S
D
W
C
K
E
Rat
Rattus norvegicus
Q5U1X1
237
26733
S92
Q
P
D
E
L
L
D
S
M
S
D
W
C
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514027
350
39624
S93
Q
P
D
E
L
L
D
S
M
S
E
W
C
K
E
Chicken
Gallus gallus
XP_417900
233
26632
S88
Q
P
D
E
L
L
D
S
M
S
E
W
C
K
E
Frog
Xenopus laevis
NP_001088822
186
21652
P52
P
N
L
I
I
K
Q
P
D
E
L
L
D
G
M
Zebra Danio
Brachydanio rerio
NP_957038
199
22942
E65
G
M
S
D
W
C
K
E
H
H
G
K
S
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCI0
211
24279
A77
K
S
E
G
P
C
F
A
I
N
H
P
Q
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780396
196
23147
I62
V
A
E
G
P
N
I
I
I
H
Q
P
D
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131502
249
28052
Q112
G
P
D
L
V
I
S
Q
S
K
D
C
L
D
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVE0
222
24913
Q88
G
P
D
L
V
V
R
Q
T
K
D
C
L
D
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
99.1
49.7
N.A.
94
94.5
N.A.
60
83.9
68.3
68.7
N.A.
42.1
N.A.
N.A.
53.5
Protein Similarity:
100
93.6
99.1
49.7
N.A.
96.1
96.6
N.A.
62.8
89.4
73.8
75.9
N.A.
59.9
N.A.
N.A.
64.5
P-Site Identity:
100
6.6
100
0
N.A.
100
100
N.A.
93.3
93.3
0
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
0
N.A.
100
100
N.A.
100
100
6.6
6.6
N.A.
40
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
42.5
N.A.
40.5
N.A.
N.A.
Protein Similarity:
N.A.
59
N.A.
56.9
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
0
15
43
0
0
% C
% Asp:
0
8
58
8
0
0
43
0
8
0
43
0
15
15
0
% D
% Glu:
0
0
15
43
0
0
0
15
0
8
15
0
0
15
43
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
22
0
0
15
0
0
0
0
8
0
8
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
8
15
8
0
0
0
0
% H
% Ile:
0
0
0
8
15
8
8
8
15
0
0
0
8
8
8
% I
% Lys:
8
0
0
0
0
8
8
0
0
15
0
8
0
43
15
% K
% Leu:
0
0
15
15
43
50
0
0
0
0
8
15
15
0
8
% L
% Met:
0
8
0
0
0
0
0
0
43
0
0
0
0
0
8
% M
% Asn:
0
8
0
8
0
8
0
0
0
8
8
0
0
0
8
% N
% Pro:
8
58
0
0
15
0
0
8
0
8
0
15
0
0
0
% P
% Gln:
43
0
0
0
0
0
8
15
0
0
8
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
8
0
0
0
8
43
8
43
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
8
0
0
0
15
8
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
43
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _