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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO2
All Species:
30
Human Site:
Y122
Identified Species:
50.77
UniProt:
Q9Y3B8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B8
NP_056338.2
237
26833
Y122
I
T
L
Q
Q
A
E
Y
E
F
L
S
F
V
R
Chimpanzee
Pan troglodytes
XP_001150488
222
25256
Y107
H
H
G
K
Q
A
E
Y
E
F
L
S
F
V
R
Rhesus Macaque
Macaca mulatta
XP_001087552
237
26863
Y122
I
T
L
Q
Q
A
E
Y
E
F
L
S
F
V
R
Dog
Lupus familis
XP_546513
121
14387
S17
S
F
V
R
Q
Q
T
S
P
G
L
C
P
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8S4
237
26720
Y122
V
T
L
Q
Q
A
E
Y
E
F
L
S
F
V
R
Rat
Rattus norvegicus
Q5U1X1
237
26733
Y122
V
T
L
Q
Q
A
E
Y
E
F
L
S
F
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514027
350
39624
Y123
I
T
L
Q
Q
A
E
Y
E
F
L
S
F
V
R
Chicken
Gallus gallus
XP_417900
233
26632
Y118
I
S
L
Q
Q
A
E
Y
E
F
L
S
F
V
R
Frog
Xenopus laevis
NP_001088822
186
21652
T82
A
V
R
E
S
R
I
T
L
Q
Q
A
E
Y
E
Zebra Danio
Brachydanio rerio
NP_957038
199
22942
R95
Y
E
F
L
S
F
I
R
Q
H
T
P
P
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCI0
211
24279
S107
G
L
I
D
R
C
K
S
S
D
V
N
L
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780396
196
23147
A92
G
L
V
D
A
V
K
A
S
K
I
T
L
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131502
249
28052
L142
E
R
V
L
Q
S
E
L
S
E
H
D
A
E
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVE0
222
24913
I118
K
K
V
L
L
S
A
I
T
E
R
E
A
E
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
99.1
49.7
N.A.
94
94.5
N.A.
60
83.9
68.3
68.7
N.A.
42.1
N.A.
N.A.
53.5
Protein Similarity:
100
93.6
99.1
49.7
N.A.
96.1
96.6
N.A.
62.8
89.4
73.8
75.9
N.A.
59.9
N.A.
N.A.
64.5
P-Site Identity:
100
73.3
100
13.3
N.A.
93.3
93.3
N.A.
100
93.3
0
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
80
100
33.3
N.A.
100
100
N.A.
100
100
13.3
6.6
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
42.5
N.A.
40.5
N.A.
N.A.
Protein Similarity:
N.A.
59
N.A.
56.9
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
50
8
8
0
0
0
8
15
0
15
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
15
0
0
0
0
0
8
0
8
0
0
0
% D
% Glu:
8
8
0
8
0
0
58
0
50
15
0
8
8
22
15
% E
% Phe:
0
8
8
0
0
8
0
0
0
50
0
0
50
0
0
% F
% Gly:
15
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% G
% His:
8
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
29
0
8
0
0
0
15
8
0
0
8
0
0
0
0
% I
% Lys:
8
8
0
8
0
0
15
0
0
8
0
0
0
0
0
% K
% Leu:
0
15
43
22
8
0
0
8
8
0
58
0
15
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
8
15
0
0
% P
% Gln:
0
0
0
43
65
8
0
0
8
8
8
0
0
8
15
% Q
% Arg:
0
8
8
8
8
8
0
8
0
0
8
0
0
0
50
% R
% Ser:
8
8
0
0
15
15
0
15
22
0
0
50
0
0
0
% S
% Thr:
0
36
0
0
0
0
8
8
8
0
8
8
0
0
0
% T
% Val:
15
8
29
0
0
8
0
0
0
0
8
0
0
50
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
50
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _