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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO2
All Species:
30.91
Human Site:
Y210
Identified Species:
52.31
UniProt:
Q9Y3B8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3B8
NP_056338.2
237
26833
Y210
S
I
K
E
L
Q
F
Y
R
N
N
I
F
K
K
Chimpanzee
Pan troglodytes
XP_001150488
222
25256
Y195
S
I
K
E
L
Q
F
Y
R
N
N
I
F
K
K
Rhesus Macaque
Macaca mulatta
XP_001087552
237
26863
Y210
S
I
K
E
L
Q
F
Y
R
N
N
I
F
K
K
Dog
Lupus familis
XP_546513
121
14387
E105
I
F
K
K
K
T
D
E
K
K
R
K
I
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8S4
237
26720
Y210
S
I
K
E
L
Q
F
Y
R
N
N
I
F
K
K
Rat
Rattus norvegicus
Q5U1X1
237
26733
Y210
S
I
K
E
L
Q
F
Y
R
N
N
I
F
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514027
350
39624
Y211
S
I
K
E
L
Q
F
Y
R
N
S
I
F
K
R
Chicken
Gallus gallus
XP_417900
233
26632
Y206
S
I
K
E
L
Q
F
Y
R
D
S
I
F
K
R
Frog
Xenopus laevis
NP_001088822
186
21652
I170
L
D
D
I
R
E
S
I
K
E
L
Q
F
Y
R
Zebra Danio
Brachydanio rerio
NP_957038
199
22942
A183
Y
R
T
S
V
F
K
A
K
E
K
K
K
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCI0
211
24279
I195
T
H
R
S
L
D
D
I
R
E
S
I
K
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780396
196
23147
I180
S
H
R
A
M
G
D
I
K
E
S
L
E
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131502
249
28052
S230
A
M
D
D
I
K
E
S
I
A
E
L
K
Y
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVE0
222
24913
S206
A
M
D
D
I
R
E
S
I
K
E
L
K
Y
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
99.1
49.7
N.A.
94
94.5
N.A.
60
83.9
68.3
68.7
N.A.
42.1
N.A.
N.A.
53.5
Protein Similarity:
100
93.6
99.1
49.7
N.A.
96.1
96.6
N.A.
62.8
89.4
73.8
75.9
N.A.
59.9
N.A.
N.A.
64.5
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
86.6
80
6.6
0
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
100
100
26.6
13.3
N.A.
46.6
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
42.5
N.A.
40.5
N.A.
N.A.
Protein Similarity:
N.A.
59
N.A.
56.9
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
22
15
0
8
22
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
50
0
8
15
8
0
29
15
0
8
15
8
% E
% Phe:
0
8
0
0
0
8
50
0
0
0
0
0
58
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
50
0
8
15
0
0
22
15
0
0
58
8
15
0
% I
% Lys:
0
0
58
8
8
8
8
0
29
15
8
15
29
50
36
% K
% Leu:
8
0
0
0
58
0
0
0
0
0
8
22
0
0
15
% L
% Met:
0
15
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
43
36
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
50
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
15
0
8
8
0
0
58
0
8
0
0
0
22
% R
% Ser:
58
0
0
15
0
0
8
15
0
0
29
0
0
0
0
% S
% Thr:
8
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
50
0
0
0
0
0
22
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _