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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPRKB
All Species:
16.97
Human Site:
S132
Identified Species:
23.33
UniProt:
Q9Y3C4
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C4
NP_057142.1
175
19661
S132
Q
V
E
G
H
Q
V
S
L
K
N
L
P
E
I
Chimpanzee
Pan troglodytes
XP_001151424
157
17708
K115
V
Y
I
E
E
G
E
K
Q
I
N
Q
E
Y
L
Rhesus Macaque
Macaca mulatta
XP_001105548
175
19571
S132
Q
V
E
G
H
Q
V
S
L
K
S
L
P
E
I
Dog
Lupus familis
XP_533004
175
19505
S132
Q
V
E
G
H
Q
V
S
L
K
N
L
P
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZZ7
175
19537
P132
Q
V
E
G
Q
Q
V
P
L
E
S
L
P
E
I
Rat
Rattus norvegicus
Q5PQR8
158
17575
Q116
Y
V
E
D
G
D
K
Q
V
H
Q
E
H
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520831
77
8512
S34
G
I
S
D
S
D
T
S
V
L
V
V
L
V
E
Chicken
Gallus gallus
XP_423597
174
19264
S132
Q
V
E
G
Q
Q
V
S
L
D
E
L
P
Q
L
Frog
Xenopus laevis
NP_001086678
175
19548
S132
Q
I
D
G
Q
Q
V
S
L
T
A
L
T
E
F
Zebra Danio
Brachydanio rerio
NP_001007374
175
19727
D132
K
V
D
G
Q
Q
I
D
V
F
Q
V
S
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500735
183
20168
L139
I
K
G
T
P
V
P
L
M
E
G
L
P
K
F
Sea Urchin
Strong. purpuratus
XP_782762
183
19688
L141
I
E
G
V
C
V
P
L
A
Q
L
S
T
H
T
Poplar Tree
Populus trichocarpa
XP_002330294
172
18708
E129
L
I
N
G
K
E
I
E
L
E
E
L
E
G
R
Maize
Zea mays
NP_001146596
172
18853
D129
L
I
S
G
T
E
I
D
L
T
E
L
E
R
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_680763
172
18808
D129
L
I
N
G
K
E
I
D
L
E
E
L
K
T
H
Baker's Yeast
Sacchar. cerevisiae
Q03705
181
20643
G131
I
M
T
S
I
V
K
G
Q
E
I
E
F
N
D
Red Bread Mold
Neurospora crassa
Q7SHG9
207
23220
E136
S
E
Q
Q
P
T
P
E
S
I
W
Q
H
L
T
Conservation
Percent
Protein Identity:
100
87.4
97.7
94.8
N.A.
85.1
70.8
N.A.
29.1
69.1
62.2
56.5
N.A.
N.A.
N.A.
34.4
37.7
Protein Similarity:
100
88.5
98.8
96.5
N.A.
93.7
84
N.A.
37.1
84
84
77.7
N.A.
N.A.
N.A.
60.6
63.3
P-Site Identity:
100
6.6
93.3
93.3
N.A.
73.3
13.3
N.A.
6.6
66.6
53.3
26.6
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
13.3
100
100
N.A.
86.6
26.6
N.A.
26.6
80
66.6
66.6
N.A.
N.A.
N.A.
33.3
6.6
Percent
Protein Identity:
29.1
34.2
N.A.
32.5
28.7
24.6
Protein Similarity:
54.2
57.1
N.A.
57.1
54.1
47.3
P-Site Identity:
20
20
N.A.
20
0
0
P-Site Similarity:
46.6
40
N.A.
46.6
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
6
0
6
0
0
0
0
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
0
12
0
18
0
6
0
0
0
6
6
% D
% Glu:
0
12
36
6
6
18
6
12
0
30
24
12
18
30
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
6
0
12
% F
% Gly:
6
0
12
59
6
6
0
6
0
0
6
0
0
6
0
% G
% His:
0
0
0
0
18
0
0
0
0
6
0
0
12
6
6
% H
% Ile:
18
30
6
0
6
0
24
0
0
12
6
0
0
0
24
% I
% Lys:
6
6
0
0
12
0
12
6
0
18
0
0
6
6
0
% K
% Leu:
18
0
0
0
0
0
0
12
53
6
6
59
6
12
12
% L
% Met:
0
6
0
0
0
0
0
0
6
0
0
0
0
0
6
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
18
0
0
6
0
% N
% Pro:
0
0
0
0
12
0
18
6
0
0
0
0
36
0
0
% P
% Gln:
36
0
6
6
24
42
0
6
12
6
12
12
0
6
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
12
% R
% Ser:
6
0
12
6
6
0
0
36
6
0
12
6
6
0
0
% S
% Thr:
0
0
6
6
6
6
6
0
0
12
0
0
12
6
12
% T
% Val:
6
42
0
6
0
18
36
0
18
0
6
12
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% W
% Tyr:
6
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _