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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPRKB
All Species:
16.36
Human Site:
S153
Identified Species:
22.5
UniProt:
Q9Y3C4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C4
NP_057142.1
175
19661
S153
K
K
I
Y
K
L
S
S
Q
E
E
S
I
G
T
Chimpanzee
Pan troglodytes
XP_001151424
157
17708
L136
H
Q
V
S
L
K
N
L
P
E
I
M
N
I
T
Rhesus Macaque
Macaca mulatta
XP_001105548
175
19571
S153
Q
K
I
Y
K
L
S
S
Q
E
E
S
I
G
T
Dog
Lupus familis
XP_533004
175
19505
S153
K
K
I
Y
K
L
S
S
Q
E
E
S
I
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZZ7
175
19537
S153
K
K
I
Y
K
L
S
S
Q
E
E
R
I
G
T
Rat
Rattus norvegicus
Q5PQR8
158
17575
P137
Q
V
P
L
E
S
L
P
E
I
T
R
L
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520831
77
8512
R55
D
R
E
G
L
A
S
R
V
E
G
Q
Q
V
S
Chicken
Gallus gallus
XP_423597
174
19264
P153
K
K
I
Y
K
I
T
P
Q
E
E
K
I
G
T
Frog
Xenopus laevis
NP_001086678
175
19548
A153
K
K
M
Y
K
L
T
A
Q
E
D
K
I
S
T
Zebra Danio
Brachydanio rerio
NP_001007374
175
19727
P153
K
K
L
Y
K
I
T
P
Q
E
D
K
C
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500735
183
20168
N160
K
K
V
Y
Q
V
G
N
P
A
F
V
E
E
G
Sea Urchin
Strong. purpuratus
XP_782762
183
19688
A162
K
K
Y
S
I
S
K
A
E
L
S
V
G
S
L
Poplar Tree
Populus trichocarpa
XP_002330294
172
18708
G150
Q
K
H
Y
K
I
S
G
L
E
A
G
L
S
S
Maize
Zea mays
NP_001146596
172
18853
P150
L
K
H
Y
K
I
P
P
Q
E
L
S
I
S
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_680763
172
18808
S150
L
K
H
Y
K
I
T
S
Q
E
L
G
I
S
S
Baker's Yeast
Sacchar. cerevisiae
Q03705
181
20643
K152
Y
D
E
A
L
I
R
K
I
Y
K
L
S
D
D
Red Bread Mold
Neurospora crassa
Q7SHG9
207
23220
E157
P
V
P
L
T
N
E
E
L
A
K
S
T
D
W
Conservation
Percent
Protein Identity:
100
87.4
97.7
94.8
N.A.
85.1
70.8
N.A.
29.1
69.1
62.2
56.5
N.A.
N.A.
N.A.
34.4
37.7
Protein Similarity:
100
88.5
98.8
96.5
N.A.
93.7
84
N.A.
37.1
84
84
77.7
N.A.
N.A.
N.A.
60.6
63.3
P-Site Identity:
100
13.3
93.3
100
N.A.
93.3
0
N.A.
13.3
73.3
60
53.3
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
26.6
N.A.
26.6
86.6
86.6
80
N.A.
N.A.
N.A.
46.6
26.6
Percent
Protein Identity:
29.1
34.2
N.A.
32.5
28.7
24.6
Protein Similarity:
54.2
57.1
N.A.
57.1
54.1
47.3
P-Site Identity:
33.3
53.3
N.A.
46.6
0
6.6
P-Site Similarity:
60
60
N.A.
66.6
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
0
6
0
12
0
12
6
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% C
% Asp:
6
6
0
0
0
0
0
0
0
0
12
0
0
12
6
% D
% Glu:
0
0
12
0
6
0
6
6
12
71
30
0
6
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
0
0
6
0
0
6
6
0
0
6
12
6
36
6
% G
% His:
6
0
18
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
30
0
6
36
0
0
6
6
6
0
48
6
0
% I
% Lys:
48
71
0
0
59
6
6
6
0
0
12
18
0
0
0
% K
% Leu:
12
0
6
12
18
30
6
6
12
6
12
6
12
0
6
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
0
0
0
6
6
6
0
0
0
0
6
0
0
% N
% Pro:
6
0
12
0
0
0
6
24
12
0
0
0
0
0
0
% P
% Gln:
18
6
0
0
6
0
0
0
53
0
0
6
6
0
0
% Q
% Arg:
0
6
0
0
0
0
6
6
0
0
0
12
0
0
0
% R
% Ser:
0
0
0
12
0
12
36
30
0
0
6
30
6
36
18
% S
% Thr:
0
0
0
0
6
0
24
0
0
0
6
0
6
0
53
% T
% Val:
0
12
12
0
0
6
0
0
6
0
0
12
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% W
% Tyr:
6
0
6
65
0
0
0
0
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _