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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPRKB All Species: 41.52
Human Site: S84 Identified Species: 57.08
UniProt: Q9Y3C4 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3C4 NP_057142.1 175 19661 S84 T E I I F N L S P N N N I S E
Chimpanzee Pan troglodytes XP_001151424 157 17708 L67 K A V H L Y K L G K M K T R T
Rhesus Macaque Macaca mulatta XP_001105548 175 19571 S84 T E I I F N L S P N N N I S E
Dog Lupus familis XP_533004 175 19505 S84 T E I I F N L S P N N N I S E
Cat Felis silvestris
Mouse Mus musculus Q8QZZ7 175 19537 S84 T E I I F N L S P N N N I S E
Rat Rattus norvegicus Q5PQR8 158 17575 G68 A V H L H K L G K M K T R T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520831 77 8512
Chicken Gallus gallus XP_423597 174 19264 S84 A E I I F N L S P N N N I S D
Frog Xenopus laevis NP_001086678 175 19548 S84 S E I L F N L S P T N N I S E
Zebra Danio Brachydanio rerio NP_001007374 175 19727 S84 S E I I F N L S P T N N I S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_500735 183 20168 S91 A E L V Y S L S P S R N I T D
Sea Urchin Strong. purpuratus XP_782762 183 19688 S93 S E I I Y S L S P S T N I S E
Poplar Tree Populus trichocarpa XP_002330294 172 18708 N81 L H S E L V Y N Y S G S K H I
Maize Zea mays NP_001146596 172 18853 N81 L H S E L V Y N Y S G S K H I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_680763 172 18808 N81 L H S E L V Y N Y S G S K H I
Baker's Yeast Sacchar. cerevisiae Q03705 181 20643 S83 S E C V L C L S P T S N I S D
Red Bread Mold Neurospora crassa Q7SHG9 207 23220 S88 S D I V I G L S P T N N I S E
Conservation
Percent
Protein Identity: 100 87.4 97.7 94.8 N.A. 85.1 70.8 N.A. 29.1 69.1 62.2 56.5 N.A. N.A. N.A. 34.4 37.7
Protein Similarity: 100 88.5 98.8 96.5 N.A. 93.7 84 N.A. 37.1 84 84 77.7 N.A. N.A. N.A. 60.6 63.3
P-Site Identity: 100 0 100 100 N.A. 100 6.6 N.A. 0 86.6 80 86.6 N.A. N.A. N.A. 40 66.6
P-Site Similarity: 100 6.6 100 100 N.A. 100 20 N.A. 0 93.3 93.3 93.3 N.A. N.A. N.A. 86.6 93.3
Percent
Protein Identity: 29.1 34.2 N.A. 32.5 28.7 24.6
Protein Similarity: 54.2 57.1 N.A. 57.1 54.1 47.3
P-Site Identity: 0 0 N.A. 0 46.6 60
P-Site Similarity: 20 20 N.A. 20 73.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 6 0 0 6 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 18 % D
% Glu: 0 59 0 18 0 0 0 0 0 0 0 0 0 0 48 % E
% Phe: 0 0 0 0 42 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 6 0 6 6 0 18 0 0 0 0 % G
% His: 0 18 6 6 6 0 0 0 0 0 0 0 0 18 0 % H
% Ile: 0 0 53 42 6 0 0 0 0 0 0 0 65 0 18 % I
% Lys: 6 0 0 0 0 6 6 0 6 6 6 6 18 0 0 % K
% Leu: 18 0 6 12 30 0 71 6 0 0 0 0 0 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 6 6 0 0 0 0 % M
% Asn: 0 0 0 0 0 42 0 18 0 30 48 65 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 6 0 6 6 0 % R
% Ser: 30 0 18 0 0 12 0 65 0 30 6 18 0 59 0 % S
% Thr: 24 0 0 0 0 0 0 0 0 24 6 6 6 12 6 % T
% Val: 0 6 6 18 0 18 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 6 18 0 18 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _