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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPRKB
All Species:
20.3
Human Site:
T37
Identified Species:
27.92
UniProt:
Q9Y3C4
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C4
NP_057142.1
175
19661
T37
R
R
K
A
M
E
G
T
I
D
G
S
L
I
N
Chimpanzee
Pan troglodytes
XP_001151424
157
17708
K24
L
L
L
F
K
D
V
K
N
A
G
D
L
R
R
Rhesus Macaque
Macaca mulatta
XP_001105548
175
19571
T37
R
R
K
A
M
E
G
T
I
D
G
S
L
I
N
Dog
Lupus familis
XP_533004
175
19505
A37
R
K
K
A
M
E
G
A
I
D
G
S
L
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZZ7
175
19537
S37
R
K
K
A
M
E
G
S
I
D
G
S
L
I
N
Rat
Rattus norvegicus
Q5PQR8
158
17575
N25
L
L
F
K
D
V
K
N
A
G
D
L
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520831
77
8512
Chicken
Gallus gallus
XP_423597
174
19264
S37
R
K
K
A
M
E
G
S
I
E
G
A
L
I
N
Frog
Xenopus laevis
NP_001086678
175
19548
S37
R
R
K
A
I
D
G
S
I
D
G
T
L
L
N
Zebra Danio
Brachydanio rerio
NP_001007374
175
19727
E37
R
K
M
A
V
N
G
E
I
K
G
A
L
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500735
183
20168
K44
S
Q
Q
L
K
E
G
K
I
D
A
A
L
I
R
Sea Urchin
Strong. purpuratus
XP_782762
183
19688
E46
K
A
M
L
I
N
K
E
L
D
A
V
M
L
S
Poplar Tree
Populus trichocarpa
XP_002330294
172
18708
E36
S
M
Q
A
G
K
L
E
P
E
V
A
F
L
N
Maize
Zea mays
NP_001146596
172
18853
E36
L
M
Q
S
G
K
L
E
P
A
V
A
L
L
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_680763
172
18808
K36
S
M
L
D
G
S
L
K
L
E
V
S
F
L
N
Baker's Yeast
Sacchar. cerevisiae
Q03705
181
20643
S36
R
S
K
M
S
E
L
S
T
S
F
A
F
I
D
Red Bread Mold
Neurospora crassa
Q7SHG9
207
23220
E41
Q
L
I
G
K
N
P
E
F
E
Y
A
F
I
D
Conservation
Percent
Protein Identity:
100
87.4
97.7
94.8
N.A.
85.1
70.8
N.A.
29.1
69.1
62.2
56.5
N.A.
N.A.
N.A.
34.4
37.7
Protein Similarity:
100
88.5
98.8
96.5
N.A.
93.7
84
N.A.
37.1
84
84
77.7
N.A.
N.A.
N.A.
60.6
63.3
P-Site Identity:
100
13.3
100
86.6
N.A.
86.6
0
N.A.
0
73.3
66.6
53.3
N.A.
N.A.
N.A.
40
6.6
P-Site Similarity:
100
20
100
93.3
N.A.
100
0
N.A.
0
100
100
73.3
N.A.
N.A.
N.A.
60
46.6
Percent
Protein Identity:
29.1
34.2
N.A.
32.5
28.7
24.6
Protein Similarity:
54.2
57.1
N.A.
57.1
54.1
47.3
P-Site Identity:
13.3
13.3
N.A.
13.3
26.6
6.6
P-Site Similarity:
46.6
46.6
N.A.
33.3
46.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
48
0
0
0
6
6
12
12
42
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
6
12
0
0
0
42
6
6
0
0
12
% D
% Glu:
0
0
0
0
0
42
0
30
0
24
0
0
0
0
0
% E
% Phe:
0
0
6
6
0
0
0
0
6
0
6
0
24
0
0
% F
% Gly:
0
0
0
6
18
0
48
0
0
6
48
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
12
0
0
0
48
0
0
0
0
53
0
% I
% Lys:
6
24
42
6
18
12
12
18
0
6
0
0
0
6
6
% K
% Leu:
18
18
12
12
0
0
24
0
12
0
0
6
59
30
0
% L
% Met:
0
18
12
6
30
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
0
0
18
0
6
6
0
0
0
0
0
59
% N
% Pro:
0
0
0
0
0
0
6
0
12
0
0
0
0
0
0
% P
% Gln:
6
6
18
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
48
18
0
0
0
0
0
0
0
0
0
0
6
6
12
% R
% Ser:
18
6
0
6
6
6
0
24
0
6
0
30
0
0
6
% S
% Thr:
0
0
0
0
0
0
0
12
6
0
0
6
0
0
0
% T
% Val:
0
0
0
0
6
6
6
0
0
0
18
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _