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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPRKB
All Species:
34.24
Human Site:
T72
Identified Species:
47.08
UniProt:
Q9Y3C4
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C4
NP_057142.1
175
19661
T72
Y
K
L
G
K
M
K
T
R
T
L
S
T
E
I
Chimpanzee
Pan troglodytes
XP_001151424
157
17708
L55
I
V
D
P
F
Q
I
L
V
A
A
N
K
A
V
Rhesus Macaque
Macaca mulatta
XP_001105548
175
19571
T72
Y
K
L
G
K
M
K
T
R
T
L
S
T
E
I
Dog
Lupus familis
XP_533004
175
19505
T72
Y
K
L
G
K
M
K
T
R
T
L
S
T
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZZ7
175
19537
T72
H
R
L
G
K
M
K
T
R
T
L
S
T
E
I
Rat
Rattus norvegicus
Q5PQR8
158
17575
V56
V
D
P
F
Q
I
L
V
A
A
N
K
A
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520831
77
8512
Chicken
Gallus gallus
XP_423597
174
19264
T72
H
K
I
G
K
M
K
T
R
T
L
N
A
E
I
Frog
Xenopus laevis
NP_001086678
175
19548
T72
Q
M
L
G
K
M
K
T
R
T
L
N
S
E
I
Zebra Danio
Brachydanio rerio
NP_001007374
175
19727
T72
H
K
I
R
K
M
K
T
R
S
L
Y
S
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500735
183
20168
C79
S
A
H
N
R
M
S
C
R
S
L
A
A
E
L
Sea Urchin
Strong. purpuratus
XP_782762
183
19688
T81
H
A
T
G
H
A
I
T
R
T
V
N
S
E
I
Poplar Tree
Populus trichocarpa
XP_002330294
172
18708
L69
I
A
K
S
R
D
S
L
T
T
R
T
L
H
S
Maize
Zea mays
NP_001146596
172
18853
L69
L
S
K
T
R
E
S
L
T
T
R
T
L
H
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_680763
172
18808
L69
I
S
K
S
R
D
S
L
S
T
R
T
L
H
S
Baker's Yeast
Sacchar. cerevisiae
Q03705
181
20643
T71
V
K
Y
N
K
M
R
T
R
N
L
N
S
E
C
Red Bread Mold
Neurospora crassa
Q7SHG9
207
23220
T76
L
T
E
G
T
L
Q
T
P
N
V
H
S
D
I
Conservation
Percent
Protein Identity:
100
87.4
97.7
94.8
N.A.
85.1
70.8
N.A.
29.1
69.1
62.2
56.5
N.A.
N.A.
N.A.
34.4
37.7
Protein Similarity:
100
88.5
98.8
96.5
N.A.
93.7
84
N.A.
37.1
84
84
77.7
N.A.
N.A.
N.A.
60.6
63.3
P-Site Identity:
100
0
100
100
N.A.
86.6
0
N.A.
0
73.3
73.3
60
N.A.
N.A.
N.A.
26.6
40
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
0
93.3
86.6
86.6
N.A.
N.A.
N.A.
53.3
66.6
Percent
Protein Identity:
29.1
34.2
N.A.
32.5
28.7
24.6
Protein Similarity:
54.2
57.1
N.A.
57.1
54.1
47.3
P-Site Identity:
6.6
6.6
N.A.
6.6
46.6
20
P-Site Similarity:
20
20
N.A.
20
66.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
18
0
0
0
6
0
0
6
12
6
6
18
6
0
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% C
% Asp:
0
6
6
0
0
12
0
0
0
0
0
0
0
6
0
% D
% Glu:
0
0
6
0
0
6
0
0
0
0
0
0
0
59
0
% E
% Phe:
0
0
0
6
6
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
48
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
24
0
6
0
6
0
0
0
0
0
0
6
0
18
6
% H
% Ile:
18
0
12
0
0
6
12
0
0
0
0
0
0
0
53
% I
% Lys:
0
36
18
0
48
0
42
0
0
0
0
6
6
0
0
% K
% Leu:
12
0
30
0
0
6
6
24
0
0
53
0
18
0
6
% L
% Met:
0
6
0
0
0
53
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
12
6
30
0
0
0
% N
% Pro:
0
0
6
6
0
0
0
0
6
0
0
0
0
0
0
% P
% Gln:
6
0
0
0
6
6
6
0
0
0
0
0
0
0
0
% Q
% Arg:
0
6
0
6
24
0
6
0
59
0
18
0
0
0
0
% R
% Ser:
6
12
0
12
0
0
24
0
6
12
0
24
30
0
18
% S
% Thr:
0
6
6
6
6
0
0
59
12
59
0
18
24
0
0
% T
% Val:
12
6
0
0
0
0
0
6
6
0
12
0
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
18
0
6
0
0
0
0
0
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _