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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPRKB
All Species:
13.33
Human Site:
Y109
Identified Species:
18.33
UniProt:
Q9Y3C4
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C4
NP_057142.1
175
19661
Y109
D
T
S
I
L
I
V
Y
I
E
E
G
E
K
Q
Chimpanzee
Pan troglodytes
XP_001151424
157
17708
A92
P
N
N
N
I
S
E
A
L
K
K
F
G
I
S
Rhesus Macaque
Macaca mulatta
XP_001105548
175
19571
Y109
D
T
S
I
L
I
V
Y
I
E
E
G
E
K
Q
Dog
Lupus familis
XP_533004
175
19505
Y109
D
T
S
V
L
I
V
Y
I
E
E
G
E
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZZ7
175
19537
Y109
N
T
S
V
L
I
V
Y
I
E
D
G
S
K
Q
Rat
Rattus norvegicus
Q5PQR8
158
17575
L93
N
N
N
I
S
E
A
L
K
K
F
G
I
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520831
77
8512
K11
S
S
R
K
V
T
E
K
T
T
V
R
S
S
Q
Chicken
Gallus gallus
XP_423597
174
19264
L109
D
T
A
V
L
I
V
L
V
V
D
R
E
K
M
Frog
Xenopus laevis
NP_001086678
175
19548
L109
D
S
G
V
L
V
V
L
T
E
D
G
T
K
T
Zebra Danio
Brachydanio rerio
NP_001007374
175
19727
L109
D
T
A
V
H
I
V
L
V
H
N
K
E
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500735
183
20168
I116
S
T
A
I
I
A
A
I
F
D
D
D
S
G
K
Sea Urchin
Strong. purpuratus
XP_782762
183
19688
V118
D
T
S
V
V
V
I
V
L
D
D
P
D
Q
T
Poplar Tree
Populus trichocarpa
XP_002330294
172
18708
A106
D
S
T
T
Y
I
L
A
A
R
F
N
A
S
P
Maize
Zea mays
NP_001146596
172
18853
A106
D
N
T
T
Y
I
L
A
A
C
F
D
A
S
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_680763
172
18808
A106
E
N
T
T
Y
I
L
A
A
R
F
N
A
S
P
Baker's Yeast
Sacchar. cerevisiae
Q03705
181
20643
K108
S
S
Q
L
I
C
L
K
F
H
T
N
T
D
D
Red Bread Mold
Neurospora crassa
Q7SHG9
207
23220
I113
K
T
R
D
V
L
V
I
K
I
V
Y
P
K
L
Conservation
Percent
Protein Identity:
100
87.4
97.7
94.8
N.A.
85.1
70.8
N.A.
29.1
69.1
62.2
56.5
N.A.
N.A.
N.A.
34.4
37.7
Protein Similarity:
100
88.5
98.8
96.5
N.A.
93.7
84
N.A.
37.1
84
84
77.7
N.A.
N.A.
N.A.
60.6
63.3
P-Site Identity:
100
0
100
93.3
N.A.
73.3
13.3
N.A.
6.6
46.6
40
33.3
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
40
N.A.
20
73.3
66.6
60
N.A.
N.A.
N.A.
46.6
80
Percent
Protein Identity:
29.1
34.2
N.A.
32.5
28.7
24.6
Protein Similarity:
54.2
57.1
N.A.
57.1
54.1
47.3
P-Site Identity:
13.3
13.3
N.A.
6.6
0
20
P-Site Similarity:
33.3
26.6
N.A.
26.6
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
18
0
0
6
12
24
18
0
0
0
18
0
0
% A
% Cys:
0
0
0
0
0
6
0
0
0
6
0
0
0
0
0
% C
% Asp:
53
0
0
6
0
0
0
0
0
12
30
12
6
6
12
% D
% Glu:
6
0
0
0
0
6
12
0
0
30
18
0
30
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
24
6
0
0
0
% F
% Gly:
0
0
6
0
0
0
0
0
0
0
0
36
6
6
0
% G
% His:
0
0
0
0
6
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
24
18
53
6
12
24
6
0
0
6
6
0
% I
% Lys:
6
0
0
6
0
0
0
12
12
12
6
6
0
42
6
% K
% Leu:
0
0
0
6
36
6
24
24
12
0
0
0
0
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% M
% Asn:
12
24
12
6
0
0
0
0
0
0
6
18
0
0
0
% N
% Pro:
6
0
0
0
0
0
0
0
0
0
0
6
6
0
12
% P
% Gln:
0
0
6
0
0
0
0
0
0
0
0
0
0
6
30
% Q
% Arg:
0
0
12
0
0
0
0
0
0
12
0
12
0
0
0
% R
% Ser:
18
24
30
0
6
6
0
0
0
0
0
0
18
30
6
% S
% Thr:
0
53
18
18
0
6
0
0
12
6
6
0
12
0
18
% T
% Val:
0
0
0
36
18
12
48
6
12
6
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
18
0
0
24
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _