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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPRKB
All Species:
7.27
Human Site:
Y121
Identified Species:
10
UniProt:
Q9Y3C4
Number Species:
16
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C4
NP_057142.1
175
19661
Y121
E
K
Q
I
N
Q
E
Y
L
I
S
Q
V
E
G
Chimpanzee
Pan troglodytes
XP_001151424
157
17708
S104
G
I
S
A
N
D
T
S
I
L
I
V
Y
I
E
Rhesus Macaque
Macaca mulatta
XP_001105548
175
19571
Y121
E
K
Q
I
N
Q
E
Y
L
I
S
Q
V
E
G
Dog
Lupus familis
XP_533004
175
19505
D121
E
K
Q
I
N
Q
E
D
L
I
S
Q
V
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZZ7
175
19537
H121
S
K
Q
V
P
Q
E
H
L
V
S
Q
V
E
G
Rat
Rattus norvegicus
Q5PQR8
158
17575
V105
I
S
E
S
N
T
S
V
L
I
V
Y
V
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520831
77
8512
F23
S
S
Q
I
S
E
A
F
K
K
F
G
I
S
D
Chicken
Gallus gallus
XP_423597
174
19264
D121
E
K
M
V
N
L
E
D
I
A
S
Q
V
E
G
Frog
Xenopus laevis
NP_001086678
175
19548
E121
T
K
T
L
Q
S
Q
E
I
I
S
Q
I
D
G
Zebra Danio
Brachydanio rerio
NP_001007374
175
19727
D121
E
E
T
L
N
I
D
D
I
I
S
K
V
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500735
183
20168
L128
S
G
K
A
M
K
K
L
A
K
A
I
K
G
T
Sea Urchin
Strong. purpuratus
XP_782762
183
19688
I130
D
Q
T
K
L
K
S
I
A
A
K
I
E
G
V
Poplar Tree
Populus trichocarpa
XP_002330294
172
18708
A118
A
S
P
D
E
M
K
A
V
E
K
L
I
N
G
Maize
Zea mays
NP_001146596
172
18853
A118
A
S
D
E
E
M
K
A
V
E
K
L
I
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_680763
172
18808
E118
A
S
P
V
E
M
E
E
V
A
K
L
I
N
G
Baker's Yeast
Sacchar. cerevisiae
Q03705
181
20643
Q120
T
D
D
V
D
K
E
Q
L
R
T
I
M
T
S
Red Bread Mold
Neurospora crassa
Q7SHG9
207
23220
S125
P
K
L
S
S
E
N
S
T
I
T
S
E
Q
Q
Conservation
Percent
Protein Identity:
100
87.4
97.7
94.8
N.A.
85.1
70.8
N.A.
29.1
69.1
62.2
56.5
N.A.
N.A.
N.A.
34.4
37.7
Protein Similarity:
100
88.5
98.8
96.5
N.A.
93.7
84
N.A.
37.1
84
84
77.7
N.A.
N.A.
N.A.
60.6
63.3
P-Site Identity:
100
6.6
100
93.3
N.A.
66.6
33.3
N.A.
13.3
60
33.3
40
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
40
N.A.
40
73.3
66.6
80
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
29.1
34.2
N.A.
32.5
28.7
24.6
Protein Similarity:
54.2
57.1
N.A.
57.1
54.1
47.3
P-Site Identity:
6.6
6.6
N.A.
13.3
13.3
13.3
P-Site Similarity:
26.6
26.6
N.A.
33.3
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
0
0
12
0
0
6
12
12
18
6
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
12
6
6
6
6
18
0
0
0
0
0
12
12
% D
% Glu:
30
6
6
6
18
12
42
12
0
12
0
0
12
36
6
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
6
0
0
0
0
% F
% Gly:
6
6
0
0
0
0
0
0
0
0
0
6
0
12
59
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
6
6
0
24
0
6
0
6
24
42
6
18
30
6
0
% I
% Lys:
0
42
6
6
0
18
18
0
6
12
24
6
6
0
0
% K
% Leu:
0
0
6
12
6
6
0
6
36
6
0
18
0
0
0
% L
% Met:
0
0
6
0
6
18
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
0
42
0
6
0
0
0
0
0
0
12
0
% N
% Pro:
6
0
12
0
6
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
6
30
0
6
24
6
6
0
0
0
36
0
6
6
% Q
% Arg:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% R
% Ser:
18
30
6
12
12
6
12
12
0
0
42
6
0
12
6
% S
% Thr:
12
0
18
0
0
6
6
0
6
0
12
0
0
6
6
% T
% Val:
0
0
0
24
0
0
0
6
18
6
6
6
42
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
6
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _