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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIL1 All Species: 16.97
Human Site: Y47 Identified Species: 31.11
UniProt: Q9Y3C6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3C6 NP_057143.1 166 18237 Y47 A E L A R R G Y Y N G T K F H
Chimpanzee Pan troglodytes XP_001173312 147 16120 R36 Y N G T K F H R I I K D F M I
Rhesus Macaque Macaca mulatta XP_001096296 130 14390 S19 P N V Y L E T S M G I V V L E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9D0W5 166 18218 Y47 A E L A R R G Y Y N G T K F H
Rat Rattus norvegicus Q812D3 161 18095 F49 F H R N I K G F M V Q T G D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509065 166 18073 Y47 A E L A R R G Y Y N G T K F H
Chicken Gallus gallus Q5ZLV2 161 18033 F49 F H R N I K G F M V Q T G D P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001029350 166 18212 Y47 A E L G R R G Y Y N S T K F H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523874 176 19507 Y56 A E L S R R G Y Y N N V V F H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52014 201 21845 E66 V E L A Q R A E G E G Y V G S
Sea Urchin Strong. purpuratus XP_780113 162 17781 K48 R G Y Y N G V K F H R I I K D
Poplar Tree Populus trichocarpa XP_002322812 164 18042 D47 L S R R G Y Y D N V K F H R I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SF72 163 17809 I48 S T V F H R I I K D F M I Q G
Conservation
Percent
Protein Identity: 100 88.5 74.6 N.A. N.A. 98.1 45.7 N.A. 95.1 45.7 N.A. 84.9 N.A. 69.8 N.A. 41.2 69.8
Protein Similarity: 100 88.5 75.9 N.A. N.A. 100 64.4 N.A. 98.1 63.2 N.A. 92.1 N.A. 80.1 N.A. 58.7 81.9
P-Site Identity: 100 0 0 N.A. N.A. 100 13.3 N.A. 100 13.3 N.A. 86.6 N.A. 73.3 N.A. 33.3 0
P-Site Similarity: 100 6.6 6.6 N.A. N.A. 100 26.6 N.A. 100 26.6 N.A. 86.6 N.A. 80 N.A. 40 13.3
Percent
Protein Identity: 65 N.A. N.A. N.A. N.A. 68
Protein Similarity: 81.9 N.A. N.A. N.A. N.A. 79.5
P-Site Identity: 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 0 N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 0 31 0 0 8 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 8 0 8 0 16 8 % D
% Glu: 0 47 0 0 0 8 0 8 0 8 0 0 0 0 8 % E
% Phe: 16 0 0 8 0 8 0 16 8 0 8 8 8 39 0 % F
% Gly: 0 8 8 8 8 8 54 0 8 8 31 0 16 8 8 % G
% His: 0 16 0 0 8 0 8 0 0 8 0 0 8 0 39 % H
% Ile: 0 0 0 0 16 0 8 8 8 8 8 8 16 0 16 % I
% Lys: 0 0 0 0 8 16 0 8 8 0 16 0 31 8 0 % K
% Leu: 8 0 47 0 8 0 0 0 0 0 0 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 24 0 0 8 0 8 0 % M
% Asn: 0 16 0 16 8 0 0 0 8 39 8 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 16 0 0 8 0 % Q
% Arg: 8 0 24 8 39 54 0 8 0 0 8 0 0 8 0 % R
% Ser: 8 8 0 8 0 0 0 8 0 0 8 0 0 0 8 % S
% Thr: 0 8 0 8 0 0 8 0 0 0 0 47 0 0 0 % T
% Val: 8 0 16 0 0 0 8 0 0 24 0 16 24 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 16 0 8 8 39 39 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _