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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED31
All Species:
52.12
Human Site:
Y108
Identified Species:
76.44
UniProt:
Q9Y3C7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C7
NP_057144.1
131
15805
Y108
Q
I
L
H
W
Q
H
Y
S
R
K
R
M
R
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103338
125
15272
Y102
Q
I
L
H
W
Q
H
Y
S
R
K
R
M
R
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXU1
131
15753
Y108
Q
I
L
H
W
Q
H
Y
S
R
K
R
V
R
L
Rat
Rattus norvegicus
NP_001129285
131
15772
Y108
Q
I
L
H
W
Q
H
Y
S
R
K
R
M
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521735
355
37889
Y332
Q
I
L
H
W
Q
H
Y
S
R
K
R
M
R
L
Chicken
Gallus gallus
XP_415924
124
15200
Y102
Q
I
L
H
W
Q
H
Y
S
R
K
R
M
R
L
Frog
Xenopus laevis
Q4QR03
128
15701
Y105
Q
I
L
H
W
Q
H
Y
S
R
K
R
V
R
L
Zebra Danio
Brachydanio rerio
Q6DH26
136
16502
Y105
Q
I
L
H
W
Q
H
Y
S
R
K
R
T
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IH24
204
23512
Y112
A
I
L
Q
W
Q
H
Y
T
R
K
R
I
K
L
Honey Bee
Apis mellifera
XP_393244
156
18762
Y125
Q
I
L
L
W
Q
H
Y
T
R
R
R
T
R
L
Nematode Worm
Caenorhab. elegans
P91869
163
19459
Y101
V
V
L
Q
W
Q
F
Y
L
R
K
R
H
R
L
Sea Urchin
Strong. purpuratus
XP_794567
223
25980
Y118
Q
L
L
H
W
Q
H
Y
T
R
R
R
M
R
L
Poplar Tree
Populus trichocarpa
XP_002321780
191
22032
Y110
Q
F
F
F
W
K
N
Y
R
N
N
R
L
K
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYB1
196
22801
Y122
Q
F
Y
Y
W
K
N
Y
R
N
N
R
L
K
H
Baker's Yeast
Sacchar. cerevisiae
P38633
127
14722
E105
G
L
L
E
G
L
D
E
L
P
K
I
I
Q
L
Red Bread Mold
Neurospora crassa
Q7SF81
134
15245
L114
S
P
D
L
V
E
R
L
R
L
E
G
M
K
A
Conservation
Percent
Protein Identity:
100
N.A.
95.4
N.A.
N.A.
97.7
97.7
N.A.
36.6
90.8
90.8
82.3
N.A.
44.6
59.6
47.8
43.5
Protein Similarity:
100
N.A.
95.4
N.A.
N.A.
100
99.2
N.A.
36.9
92.3
94.6
87.5
N.A.
55.8
69.8
61.3
51.1
P-Site Identity:
100
N.A.
100
N.A.
N.A.
93.3
100
N.A.
100
100
93.3
93.3
N.A.
66.6
73.3
60
80
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
86.6
86.6
66.6
100
Percent
Protein Identity:
32.4
N.A.
N.A.
35.2
32.8
38
Protein Similarity:
45.5
N.A.
N.A.
47.9
50.3
54.4
P-Site Identity:
26.6
N.A.
N.A.
26.6
20
6.6
P-Site Similarity:
53.3
N.A.
N.A.
60
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
0
7
0
7
0
0
7
0
0
0
0
% E
% Phe:
0
13
7
7
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
57
0
0
69
0
0
0
0
0
7
0
13
% H
% Ile:
0
63
0
0
0
0
0
0
0
0
0
7
13
0
0
% I
% Lys:
0
0
0
0
0
13
0
0
0
0
69
0
0
25
0
% K
% Leu:
0
13
82
13
0
7
0
7
13
7
0
0
13
0
82
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
44
0
0
% M
% Asn:
0
0
0
0
0
0
13
0
0
13
13
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
75
0
0
13
0
75
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
7
0
19
75
13
88
0
69
0
% R
% Ser:
7
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
19
0
0
0
13
0
0
% T
% Val:
7
7
0
0
7
0
0
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
88
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
0
0
88
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _