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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED31
All Species:
47.58
Human Site:
Y81
Identified Species:
69.78
UniProt:
Q9Y3C7
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3C7
NP_057144.1
131
15805
Y81
H
M
L
E
L
L
Q
Y
E
H
F
R
K
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103338
125
15272
Y75
H
M
L
E
L
L
Q
Y
E
H
F
R
K
E
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXU1
131
15753
Y81
H
M
L
E
L
L
Q
Y
E
H
F
R
K
E
L
Rat
Rattus norvegicus
NP_001129285
131
15772
Y81
H
M
L
E
L
L
Q
Y
E
H
F
R
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521735
355
37889
Y305
H
M
L
E
L
L
Q
Y
E
H
F
R
K
E
L
Chicken
Gallus gallus
XP_415924
124
15200
Y75
H
M
L
E
L
L
Q
Y
E
H
F
R
K
E
L
Frog
Xenopus laevis
Q4QR03
128
15701
Y78
H
M
L
E
L
L
Q
Y
E
H
F
R
K
E
L
Zebra Danio
Brachydanio rerio
Q6DH26
136
16502
Y78
H
M
L
E
L
L
Q
Y
E
H
F
R
K
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IH24
204
23512
Y85
Y
F
L
D
L
L
Q
Y
E
H
F
R
R
E
I
Honey Bee
Apis mellifera
XP_393244
156
18762
Y98
Y
F
L
D
L
L
Q
Y
E
H
F
R
R
E
V
Nematode Worm
Caenorhab. elegans
P91869
163
19459
S74
H
M
L
E
A
L
Q
S
Q
Q
F
R
D
S
M
Sea Urchin
Strong. purpuratus
XP_794567
223
25980
Y91
H
F
L
E
L
L
Q
Y
E
H
F
R
R
E
L
Poplar Tree
Populus trichocarpa
XP_002321780
191
22032
N83
Y
F
L
E
L
L
Q
N
A
N
F
R
N
A
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VYB1
196
22801
N95
Y
F
L
E
L
L
Q
N
P
N
F
R
T
A
M
Baker's Yeast
Sacchar. cerevisiae
P38633
127
14722
G87
F
I
L
K
L
L
N
G
F
M
E
S
A
I
V
Red Bread Mold
Neurospora crassa
Q7SF81
134
15245
Q97
L
K
N
L
E
L
L
Q
Q
E
K
F
R
Q
D
Conservation
Percent
Protein Identity:
100
N.A.
95.4
N.A.
N.A.
97.7
97.7
N.A.
36.6
90.8
90.8
82.3
N.A.
44.6
59.6
47.8
43.5
Protein Similarity:
100
N.A.
95.4
N.A.
N.A.
100
99.2
N.A.
36.9
92.3
94.6
87.5
N.A.
55.8
69.8
61.3
51.1
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
100
100
100
N.A.
66.6
66.6
53.3
86.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
93.3
66.6
93.3
Percent
Protein Identity:
32.4
N.A.
N.A.
35.2
32.8
38
Protein Similarity:
45.5
N.A.
N.A.
47.9
50.3
54.4
P-Site Identity:
46.6
N.A.
N.A.
46.6
20
6.6
P-Site Similarity:
66.6
N.A.
N.A.
66.6
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
7
0
0
0
7
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
0
0
0
0
0
0
0
0
7
0
7
% D
% Glu:
0
0
0
75
7
0
0
0
69
7
7
0
0
69
0
% E
% Phe:
7
32
0
0
0
0
0
0
7
0
88
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
63
0
0
0
0
0
0
0
0
69
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
7
% I
% Lys:
0
7
0
7
0
0
0
0
0
0
7
0
50
0
0
% K
% Leu:
7
0
94
7
88
100
7
0
0
0
0
0
0
0
57
% L
% Met:
0
57
0
0
0
0
0
0
0
7
0
0
0
0
19
% M
% Asn:
0
0
7
0
0
0
7
13
0
13
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
88
7
13
7
0
0
0
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
88
25
0
0
% R
% Ser:
0
0
0
0
0
0
0
7
0
0
0
7
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
0
0
0
0
0
69
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _