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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FIS1
All Species:
19.09
Human Site:
S23
Identified Species:
42
UniProt:
Q9Y3D6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3D6
NP_057152.2
152
16938
S23
K
F
E
K
K
F
Q
S
E
K
A
A
G
S
V
Chimpanzee
Pan troglodytes
XP_001143081
396
42666
S267
K
F
E
K
K
F
Q
S
E
K
A
A
G
S
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536854
152
16877
S23
K
F
E
K
K
F
Q
S
E
K
A
A
G
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ92
152
16990
S23
N
F
E
R
K
F
Q
S
E
Q
A
A
G
S
V
Rat
Rattus norvegicus
P84817
152
16976
S23
N
F
E
R
K
F
Q
S
E
Q
A
A
G
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090116
151
16898
A23
K
F
E
K
K
Y
L
A
E
R
Q
I
G
S
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137608
148
16969
E24
F
E
K
K
Y
H
H
E
L
E
L
D
G
E
V
Honey Bee
Apis mellifera
XP_623649
150
17139
E23
K
F
E
R
I
Y
N
E
Q
L
R
S
S
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194605
177
19882
A51
K
H
E
Q
L
Y
N
A
E
L
A
Q
G
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40515
155
17715
V30
E
I
L
R
Q
Q
V
V
S
E
G
G
P
T
A
Red Bread Mold
Neurospora crassa
Q7S8M1
153
16905
Y26
L
N
V
L
R
A
Q
Y
E
K
E
G
E
M
V
Conservation
Percent
Protein Identity:
100
38.3
N.A.
98.6
N.A.
96
96.7
N.A.
N.A.
N.A.
76.3
N.A.
N.A.
47.3
53.2
N.A.
50.2
Protein Similarity:
100
38.3
N.A.
99.3
N.A.
98.6
98.6
N.A.
N.A.
N.A.
90.1
N.A.
N.A.
67.1
71
N.A.
67.2
P-Site Identity:
100
100
N.A.
100
N.A.
80
80
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
20
20
N.A.
40
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
80
N.A.
N.A.
33.3
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.3
35.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.9
55.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
19
0
0
55
46
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
10
73
0
0
0
0
19
73
19
10
0
10
10
0
% E
% Phe:
10
64
0
0
0
46
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
19
73
0
0
% G
% His:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
55
0
10
46
55
0
0
0
0
37
0
0
0
0
0
% K
% Leu:
10
0
10
10
10
0
10
0
10
19
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
19
10
0
0
0
0
19
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
10
10
10
55
0
10
19
10
10
0
0
0
% Q
% Arg:
0
0
0
37
10
0
0
0
0
10
10
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
46
10
0
0
10
10
55
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
10
0
0
0
10
10
0
0
0
0
0
10
73
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
28
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _