Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIS1 All Species: 35.15
Human Site: Y47 Identified Species: 77.33
UniProt: Q9Y3D6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3D6 NP_057152.2 152 16938 Y47 W C L V R S K Y N D D I R K G
Chimpanzee Pan troglodytes XP_001143081 396 42666 Y291 W C L V R S K Y N D D I R K G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536854 152 16877 Y47 W C L V R S K Y N D D I R K G
Cat Felis silvestris
Mouse Mus musculus Q9CQ92 152 16990 Y47 W C L V R S K Y N E D I R R G
Rat Rattus norvegicus P84817 152 16976 Y47 W C L V R S K Y N D D I R R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001090116 151 16898 Y47 W C L I R S K Y N D D I K K G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137608 148 16969 Y48 F C L V R S R Y T N D V R K G
Honey Bee Apis mellifera XP_623649 150 17139 Y47 W C L V R S K Y P A D I R K G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194605 177 19882 Y75 W C L V R S R Y R D D M R R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40515 155 17715 D54 W G L I K S T D V N D E R L G
Red Bread Mold Neurospora crassa Q7S8M1 153 16905 V50 W G L V K S N V R A D Q H L G
Conservation
Percent
Protein Identity: 100 38.3 N.A. 98.6 N.A. 96 96.7 N.A. N.A. N.A. 76.3 N.A. N.A. 47.3 53.2 N.A. 50.2
Protein Similarity: 100 38.3 N.A. 99.3 N.A. 98.6 98.6 N.A. N.A. N.A. 90.1 N.A. N.A. 67.1 71 N.A. 67.2
P-Site Identity: 100 100 N.A. 100 N.A. 86.6 93.3 N.A. N.A. N.A. 86.6 N.A. N.A. 66.6 86.6 N.A. 73.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. N.A. 100 N.A. N.A. 93.3 86.6 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.3 35.2
Protein Similarity: N.A. N.A. N.A. N.A. 50.9 55.5
P-Site Identity: N.A. N.A. N.A. N.A. 40 40
P-Site Similarity: N.A. N.A. N.A. N.A. 60 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % A
% Cys: 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 55 100 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 100 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 19 0 0 0 0 0 0 0 64 0 0 0 % I
% Lys: 0 0 0 0 19 0 64 0 0 0 0 0 10 55 0 % K
% Leu: 0 0 100 0 0 0 0 0 0 0 0 0 0 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 55 19 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 82 0 19 0 19 0 0 0 82 28 0 % R
% Ser: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 82 0 0 0 10 10 0 0 10 0 0 0 % V
% Trp: 91 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _