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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AK6 All Species: 30.3
Human Site: Y31 Identified Species: 55.56
UniProt: Q9Y3D8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3D8 NP_001015891.1 172 20061 Y31 A S K S G L K Y I N V G D L A
Chimpanzee Pan troglodytes XP_001145727 104 12543
Rhesus Macaque Macaca mulatta XP_001093722 171 20047 Y30 A S K S G L K Y I N V G D L A
Dog Lupus familis XP_535264 290 32045 Y149 A S R S G L K Y I N V G D L A
Cat Felis silvestris
Mouse Mus musculus Q8VCP8 172 19929 Y31 A S R S G L K Y V N V G D L A
Rat Rattus norvegicus Q5EB68 172 19926 Y31 A S R S G L K Y V N V G D L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512366 172 20206 Y32 A S R T E L N Y V N V G D L A
Chicken Gallus gallus NP_001026504 171 20053 Y31 A S R T G L T Y I S V G D L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002118 171 19818 Y31 A Q R T G L T Y V N V G D L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394153 177 20763 W36 S E K T G L A W I D V S K F A
Nematode Worm Caenorhab. elegans Q09527 182 21006 F37 A E K L G F V F I E V S K E V
Sea Urchin Strong. purpuratus XP_799000 161 18783 E30 N V G D V A K E K E L Y E G W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12055 197 22705 K35 K N K L K D Y K Y Y N I S D F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.6 95.3 53 N.A. 87.7 86 N.A. 79 77.3 N.A. 75 N.A. N.A. 55.3 45.5 54.6
Protein Similarity: 100 56.9 96.5 57.2 N.A. 94.7 93 N.A. 91.2 90.6 N.A. 88.3 N.A. N.A. 72.3 67.5 72.6
P-Site Identity: 100 0 100 93.3 N.A. 86.6 86.6 N.A. 66.6 73.3 N.A. 66.6 N.A. N.A. 40 33.3 6.6
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 86.6 93.3 N.A. 86.6 N.A. N.A. 66.6 40 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 56.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 70 0 0 0 0 8 8 0 0 0 0 0 0 0 70 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 0 8 0 0 62 8 0 % D
% Glu: 0 16 0 0 8 0 0 8 0 16 0 0 8 8 0 % E
% Phe: 0 0 0 0 0 8 0 8 0 0 0 0 0 8 8 % F
% Gly: 0 0 8 0 70 0 0 0 0 0 0 62 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 47 0 0 8 0 0 0 % I
% Lys: 8 0 39 0 8 0 47 8 8 0 0 0 16 0 0 % K
% Leu: 0 0 0 16 0 70 0 0 0 0 8 0 0 62 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 0 0 0 8 0 0 54 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 54 0 39 0 0 0 0 0 8 0 16 8 0 0 % S
% Thr: 0 0 0 31 0 0 16 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 0 8 0 8 0 31 0 77 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 8 62 8 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _