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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO7
All Species:
22.12
Human Site:
S189
Identified Species:
54.07
UniProt:
Q9Y3I1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3I1
NP_001028196.1
522
58503
S189
S
L
E
T
L
Y
Q
S
A
D
C
S
D
A
N
Chimpanzee
Pan troglodytes
XP_001153721
522
58521
S189
S
L
E
T
L
Y
Q
S
A
D
C
S
D
A
N
Rhesus Macaque
Macaca mulatta
XP_001112612
522
58391
S189
S
L
E
T
L
Y
Q
S
A
D
C
S
D
A
N
Dog
Lupus familis
XP_531752
634
69677
S300
S
L
E
I
L
Y
Q
S
A
D
C
S
N
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3U7U3
523
57650
S189
S
L
E
T
L
Y
Q
S
A
G
C
S
N
I
S
Rat
Rattus norvegicus
Q68FS3
522
57542
S189
S
L
E
A
L
Y
Q
S
A
G
C
S
T
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508986
519
58332
E182
E
T
L
Y
H
S
A
E
C
T
G
T
N
D
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086668
478
53233
I185
S
D
A
F
I
V
V
I
H
L
L
M
L
E
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779952
545
59552
E212
R
L
K
E
L
C
E
E
I
Q
P
E
N
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZUB9
350
39935
S57
K
N
V
L
L
E
K
S
G
D
T
S
D
L
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.4
66.2
N.A.
72.8
72.6
N.A.
66
N.A.
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
28.4
Protein Similarity:
100
99.2
97.6
72
N.A.
83.3
83.5
N.A.
75.6
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
100
100
80
N.A.
73.3
66.6
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
73.3
N.A.
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
10
0
60
0
0
0
0
30
10
% A
% Cys:
0
0
0
0
0
10
0
0
10
0
60
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
50
0
0
40
10
0
% D
% Glu:
10
0
60
10
0
10
10
20
0
0
0
10
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
20
10
0
0
0
10
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
10
10
0
0
0
0
10
0
% I
% Lys:
10
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
70
10
10
80
0
0
0
0
10
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
40
0
40
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
60
0
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
70
0
0
0
0
10
0
70
0
0
0
70
0
10
20
% S
% Thr:
0
10
0
40
0
0
0
0
0
10
10
10
10
0
20
% T
% Val:
0
0
10
0
0
10
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
60
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _