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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO7
All Species:
13.94
Human Site:
S436
Identified Species:
34.07
UniProt:
Q9Y3I1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3I1
NP_001028196.1
522
58503
S436
L
H
P
R
P
F
P
S
S
R
L
P
P
G
I
Chimpanzee
Pan troglodytes
XP_001153721
522
58521
S436
L
H
P
R
P
F
P
S
S
R
L
P
P
G
I
Rhesus Macaque
Macaca mulatta
XP_001112612
522
58391
S436
L
H
P
R
P
F
P
S
S
R
L
P
P
G
I
Dog
Lupus familis
XP_531752
634
69677
P547
W
H
P
R
P
F
P
P
S
S
L
L
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3U7U3
523
57650
T437
Y
P
R
A
Y
L
P
T
S
L
L
P
P
G
I
Rat
Rattus norvegicus
Q68FS3
522
57542
T436
Y
P
R
P
Y
L
P
T
T
L
L
P
P
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508986
519
58332
P427
F
Y
P
S
P
F
P
P
N
P
F
S
P
N
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086668
478
53233
P414
Y
Y
P
N
V
F
P
P
D
I
N
Y
P
P
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779952
545
59552
G445
P
V
P
L
P
L
P
G
I
Y
P
P
G
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZUB9
350
39935
L286
W
R
R
K
R
L
D
L
L
A
R
R
N
P
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.4
66.2
N.A.
72.8
72.6
N.A.
66
N.A.
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
28.4
Protein Similarity:
100
99.2
97.6
72
N.A.
83.3
83.5
N.A.
75.6
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
100
100
60
N.A.
46.6
40
N.A.
33.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
60
N.A.
53.3
53.3
N.A.
46.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
60
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
10
50
20
% G
% His:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
50
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
30
0
0
10
0
40
0
10
10
20
60
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
0
10
0
10
10
0
% N
% Pro:
10
20
70
10
60
0
90
30
0
10
10
60
80
30
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
30
40
10
0
0
0
0
30
10
10
0
0
10
% R
% Ser:
0
0
0
10
0
0
0
30
50
10
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
20
10
0
0
0
0
0
0
% T
% Val:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
30
20
0
0
20
0
0
0
0
10
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _