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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO7
All Species:
13.64
Human Site:
S473
Identified Species:
33.33
UniProt:
Q9Y3I1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3I1
NP_001028196.1
522
58503
S473
P
G
P
G
E
T
P
S
Q
F
P
P
L
R
P
Chimpanzee
Pan troglodytes
XP_001153721
522
58521
S473
P
G
P
G
E
T
P
S
Q
F
A
P
L
R
P
Rhesus Macaque
Macaca mulatta
XP_001112612
522
58391
S473
P
G
P
G
E
T
P
S
Q
F
P
P
L
R
P
Dog
Lupus familis
XP_531752
634
69677
P584
I
P
G
P
G
E
T
P
S
Q
F
P
P
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3U7U3
523
57650
G474
P
R
P
G
E
L
P
G
Q
F
R
P
L
R
P
Rat
Rattus norvegicus
Q68FS3
522
57542
S473
P
R
P
G
E
P
P
S
Q
F
R
P
V
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508986
519
58332
N464
P
I
N
S
L
I
P
N
P
G
E
T
R
G
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086668
478
53233
S451
F
K
V
T
L
P
F
S
E
N
D
P
S
I
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779952
545
59552
R482
F
Q
P
I
P
G
P
R
H
D
P
I
F
P
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZUB9
350
39935
F323
D
R
F
G
P
S
D
F
Y
R
F
G
L
R
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.4
66.2
N.A.
72.8
72.6
N.A.
66
N.A.
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
28.4
Protein Similarity:
100
99.2
97.6
72
N.A.
83.3
83.5
N.A.
75.6
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
93.3
100
6.6
N.A.
73.3
73.3
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
100
6.6
N.A.
73.3
80
N.A.
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
10
10
0
0
0
10
% D
% Glu:
0
0
0
0
50
10
0
0
10
0
10
0
0
0
0
% E
% Phe:
20
0
10
0
0
0
10
10
0
50
20
0
10
0
0
% F
% Gly:
0
30
10
60
10
10
0
10
0
10
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% H
% Ile:
10
10
0
10
0
10
0
0
0
0
0
10
0
10
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
20
10
0
0
0
0
0
0
50
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
10
% N
% Pro:
60
10
60
10
20
20
70
10
10
0
30
70
10
10
60
% P
% Gln:
0
10
0
0
0
0
0
0
50
10
0
0
0
0
0
% Q
% Arg:
0
30
0
0
0
0
0
10
0
10
20
0
10
60
10
% R
% Ser:
0
0
0
10
0
10
0
50
10
0
0
0
10
0
0
% S
% Thr:
0
0
0
10
0
30
10
0
0
0
0
10
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _