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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO7
All Species:
8.79
Human Site:
Y425
Identified Species:
21.48
UniProt:
Q9Y3I1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3I1
NP_001028196.1
522
58503
Y425
S
T
H
T
I
P
F
Y
P
N
P
L
H
P
R
Chimpanzee
Pan troglodytes
XP_001153721
522
58521
Y425
S
T
H
T
I
P
F
Y
P
N
P
L
H
P
R
Rhesus Macaque
Macaca mulatta
XP_001112612
522
58391
Y425
S
T
H
G
I
P
F
Y
P
N
P
L
H
P
R
Dog
Lupus familis
XP_531752
634
69677
G536
S
P
H
P
I
P
F
G
P
S
P
W
H
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3U7U3
523
57650
P426
A
H
P
I
P
F
C
P
I
P
V
Y
P
R
A
Rat
Rattus norvegicus
Q68FS3
522
57542
P425
V
H
P
I
P
F
C
P
I
P
V
Y
P
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508986
519
58332
H416
Q
P
H
P
I
P
F
H
P
N
P
F
Y
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086668
478
53233
H403
F
L
P
P
R
N
A
H
P
Y
P
Y
Y
P
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779952
545
59552
A434
P
P
G
R
R
P
F
A
F
V
P
P
V
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZUB9
350
39935
F275
D
V
D
W
K
R
K
F
A
S
F
W
R
R
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
95.4
66.2
N.A.
72.8
72.6
N.A.
66
N.A.
46.5
N.A.
N.A.
N.A.
N.A.
N.A.
28.4
Protein Similarity:
100
99.2
97.6
72
N.A.
83.3
83.5
N.A.
75.6
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
100
93.3
66.6
N.A.
0
0
N.A.
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
6.6
0
N.A.
66.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
10
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
20
60
10
10
0
10
10
0
0
0
% F
% Gly:
0
0
10
10
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
20
50
0
0
0
0
20
0
0
0
0
40
0
0
% H
% Ile:
0
0
0
20
50
0
0
0
20
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
30
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
40
0
0
0
0
10
% N
% Pro:
10
30
30
30
20
60
0
20
60
20
70
10
20
70
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
20
10
0
0
0
0
0
0
10
30
40
% R
% Ser:
40
0
0
0
0
0
0
0
0
20
0
0
0
0
10
% S
% Thr:
0
30
0
20
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
10
0
0
0
0
0
0
0
10
20
0
10
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
20
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
0
10
0
30
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _