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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED3
All Species:
12.12
Human Site:
S8
Identified Species:
22.22
UniProt:
Q9Y3Q3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Q3
NP_031390.1
217
24777
S8
M
G
S
T
V
P
R
S
A
S
V
L
L
L
L
Chimpanzee
Pan troglodytes
XP_001153825
217
24768
S8
M
G
S
T
V
P
R
S
A
S
V
L
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001109063
219
24908
S8
M
G
S
A
A
P
L
S
A
S
V
L
L
L
L
Dog
Lupus familis
XP_858610
226
25282
L21
A
G
R
W
G
C
R
L
L
A
L
L
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
A8
M
V
H
E
A
P
H
A
S
S
F
Q
M
L
L
Rat
Rattus norvegicus
Q6AY25
221
25492
A8
M
G
N
E
V
P
R
A
S
S
F
Q
M
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
S66
F
P
T
A
L
K
H
S
F
S
Q
I
V
Y
I
Chicken
Gallus gallus
XP_413948
205
23206
W8
M
R
G
W
M
R
G
W
A
L
A
L
L
L
G
Frog
Xenopus laevis
NP_001087434
219
25215
W13
Y
L
V
K
E
F
R
W
W
S
F
L
S
F
M
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
W9
A
G
S
S
L
S
S
W
L
L
P
L
F
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17528
203
22968
L8
M
N
S
L
T
W
I
L
A
V
L
F
V
T
P
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
S9
C
E
I
T
L
F
L
S
I
F
V
A
L
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
P9
I
K
S
T
I
A
L
P
S
F
F
I
V
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.3
64.1
N.A.
88.6
91.4
N.A.
42.4
68.6
62
62.2
N.A.
N.A.
N.A.
27.1
52.5
Protein Similarity:
100
99
96.8
77.8
N.A.
92.3
95
N.A.
51.8
77.8
75.8
80.6
N.A.
N.A.
N.A.
45.1
69.5
P-Site Identity:
100
100
80
40
N.A.
33.3
46.6
N.A.
13.3
33.3
20
20
N.A.
N.A.
N.A.
20
33.3
P-Site Similarity:
100
100
80
53.3
N.A.
53.3
80
N.A.
46.6
40
26.6
40
N.A.
N.A.
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
16
16
8
0
16
39
8
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
16
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
16
0
0
8
16
31
8
8
8
0
% F
% Gly:
0
47
8
0
8
0
8
0
0
0
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
16
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
8
0
8
0
8
0
0
16
0
0
16
% I
% Lys:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
24
0
24
16
16
16
16
54
47
62
47
% L
% Met:
54
0
0
0
8
0
0
0
0
0
0
0
16
0
16
% M
% Asn:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
39
0
8
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
16
0
0
8
% Q
% Arg:
0
8
8
0
0
8
39
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
47
8
0
8
8
39
24
54
0
0
8
0
0
% S
% Thr:
0
0
8
31
8
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
8
8
0
24
0
0
0
0
8
31
0
24
8
0
% V
% Trp:
0
0
0
16
0
8
0
24
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _