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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED3
All Species:
40.3
Human Site:
T159
Identified Species:
73.89
UniProt:
Q9Y3Q3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Q3
NP_031390.1
217
24777
T159
K
T
V
I
D
S
Q
T
H
Y
R
L
R
E
A
Chimpanzee
Pan troglodytes
XP_001153825
217
24768
T159
K
T
V
I
D
S
Q
T
H
Y
R
L
R
E
A
Rhesus Macaque
Macaca mulatta
XP_001109063
219
24908
T161
K
T
V
I
D
S
Q
T
H
Y
R
L
R
E
A
Dog
Lupus familis
XP_858610
226
25282
T168
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
T163
K
T
V
I
D
S
Q
T
H
Y
R
L
R
E
A
Rat
Rattus norvegicus
Q6AY25
221
25492
T163
K
T
V
I
D
S
Q
T
H
Y
R
L
R
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
T274
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Chicken
Gallus gallus
XP_413948
205
23206
V149
I
H
E
A
L
N
A
V
I
D
S
Q
T
H
Y
Frog
Xenopus laevis
NP_001087434
219
25215
T161
K
S
V
I
D
Y
Q
T
H
F
R
L
R
E
A
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
T159
K
S
V
M
D
Y
Q
T
H
F
R
L
R
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17528
203
22968
M144
R
E
L
S
S
A
L
M
S
V
K
H
E
Q
E
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
T155
K
A
V
V
N
F
Q
T
H
Y
R
L
R
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
T159
N
L
N
K
I
T
K
T
L
N
Y
L
R
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.3
64.1
N.A.
88.6
91.4
N.A.
42.4
68.6
62
62.2
N.A.
N.A.
N.A.
27.1
52.5
Protein Similarity:
100
99
96.8
77.8
N.A.
92.3
95
N.A.
51.8
77.8
75.8
80.6
N.A.
N.A.
N.A.
45.1
69.5
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
80
0
80
73.3
N.A.
N.A.
N.A.
0
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
6.6
93.3
93.3
N.A.
N.A.
N.A.
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
8
0
0
0
0
0
0
8
70
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
70
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
8
8
0
0
0
0
0
0
0
0
0
8
77
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
31
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
77
0
0
8
0
8
0
% H
% Ile:
8
0
0
62
8
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
77
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% K
% Leu:
0
8
8
0
8
0
8
0
8
0
0
85
0
0
0
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
8
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
77
0
0
0
0
8
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
77
0
85
0
8
% R
% Ser:
0
31
0
8
8
39
0
0
8
0
8
0
0
0
0
% S
% Thr:
0
39
0
0
0
8
0
85
0
0
0
0
8
0
0
% T
% Val:
0
0
77
8
0
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
31
0
0
0
47
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _