KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED3
All Species:
36.36
Human Site:
T89
Identified Species:
66.67
UniProt:
Q9Y3Q3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Q3
NP_031390.1
217
24777
T89
K
K
Q
Y
D
S
F
T
Y
R
A
E
V
K
G
Chimpanzee
Pan troglodytes
XP_001153825
217
24768
T89
K
K
Q
Y
D
S
F
T
Y
R
A
E
V
K
G
Rhesus Macaque
Macaca mulatta
XP_001109063
219
24908
T91
K
K
Q
Y
D
S
F
T
Y
R
A
E
V
K
G
Dog
Lupus familis
XP_858610
226
25282
T99
K
K
Q
Y
D
S
F
T
F
T
A
S
K
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
T93
K
K
Q
Y
D
S
F
T
Y
K
T
E
A
K
G
Rat
Rattus norvegicus
Q6AY25
221
25492
T93
K
K
Q
Y
D
S
F
T
Y
K
T
E
V
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
T205
K
K
Q
Y
D
S
F
T
F
T
A
S
R
N
G
Chicken
Gallus gallus
XP_413948
205
23206
P84
K
K
Q
Y
D
S
F
P
H
H
T
E
L
T
G
Frog
Xenopus laevis
NP_001087434
219
25215
T92
K
K
Q
Y
D
S
F
T
F
T
A
T
R
N
G
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
T90
K
K
Q
Y
D
S
F
T
F
S
A
A
R
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17528
203
22968
T79
R
E
S
S
G
K
F
T
F
A
A
H
M
D
G
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
T85
R
K
Q
Y
D
T
F
T
W
T
T
D
Q
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
L93
Q
K
K
Y
S
D
F
L
L
K
S
F
G
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.3
64.1
N.A.
88.6
91.4
N.A.
42.4
68.6
62
62.2
N.A.
N.A.
N.A.
27.1
52.5
Protein Similarity:
100
99
96.8
77.8
N.A.
92.3
95
N.A.
51.8
77.8
75.8
80.6
N.A.
N.A.
N.A.
45.1
69.5
P-Site Identity:
100
100
100
66.6
N.A.
80
86.6
N.A.
66.6
60
66.6
66.6
N.A.
N.A.
N.A.
26.6
46.6
P-Site Similarity:
100
100
100
73.3
N.A.
86.6
93.3
N.A.
73.3
73.3
73.3
73.3
N.A.
N.A.
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
62
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
85
8
0
0
0
0
0
8
0
8
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
47
0
0
0
% E
% Phe:
0
0
0
0
0
0
100
0
39
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
100
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
77
93
8
0
0
8
0
0
0
24
0
0
8
39
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
0
85
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
16
0
0
0
0
0
0
0
0
24
0
0
24
0
0
% R
% Ser:
0
0
8
8
8
77
0
0
0
8
8
16
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
85
0
31
31
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
31
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
93
0
0
0
0
39
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _