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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED3
All Species:
44.24
Human Site:
Y115
Identified Species:
81.11
UniProt:
Q9Y3Q3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Q3
NP_031390.1
217
24777
Y115
T
F
S
H
K
T
V
Y
F
D
F
Q
V
G
D
Chimpanzee
Pan troglodytes
XP_001153825
217
24768
Y115
T
F
S
H
K
T
V
Y
F
D
F
Q
V
G
D
Rhesus Macaque
Macaca mulatta
XP_001109063
219
24908
Y117
T
F
S
H
K
T
V
Y
F
D
F
Q
V
G
D
Dog
Lupus familis
XP_858610
226
25282
Y125
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
Y119
T
F
S
H
K
T
V
Y
F
D
F
Q
V
G
D
Rat
Rattus norvegicus
Q6AY25
221
25492
Y119
T
F
S
H
K
T
V
Y
F
D
F
Q
V
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
Y231
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
E
Chicken
Gallus gallus
XP_413948
205
23206
Y110
T
F
S
H
K
T
V
Y
F
N
L
Q
V
G
D
Frog
Xenopus laevis
NP_001087434
219
25215
Y118
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
D
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
Y116
T
F
T
H
K
T
V
Y
F
D
F
Q
V
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17528
203
22968
M105
T
M
T
P
K
A
V
M
F
T
V
E
I
T
E
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
Y111
T
F
A
H
K
V
V
Y
F
D
F
M
A
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
I119
T
A
L
K
K
V
E
I
T
L
E
K
E
K
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.3
64.1
N.A.
88.6
91.4
N.A.
42.4
68.6
62
62.2
N.A.
N.A.
N.A.
27.1
52.5
Protein Similarity:
100
99
96.8
77.8
N.A.
92.3
95
N.A.
51.8
77.8
75.8
80.6
N.A.
N.A.
N.A.
45.1
69.5
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
86.6
86.6
93.3
93.3
N.A.
N.A.
N.A.
26.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
100
N.A.
N.A.
N.A.
53.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
70
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
8
8
8
0
24
% E
% Phe:
0
85
0
0
0
0
0
0
93
0
77
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
85
0
% G
% His:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
8
100
0
0
0
0
0
0
8
0
8
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
8
8
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
77
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
100
0
39
0
0
77
0
0
8
8
0
0
0
8
8
% T
% Val:
0
0
0
0
0
16
93
0
0
0
8
0
77
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _