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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMED3
All Species:
38.48
Human Site:
Y98
Identified Species:
70.56
UniProt:
Q9Y3Q3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Q3
NP_031390.1
217
24777
Y98
R
A
E
V
K
G
V
Y
Q
F
C
F
S
N
E
Chimpanzee
Pan troglodytes
XP_001153825
217
24768
Y98
R
A
E
V
K
G
V
Y
Q
F
C
F
S
N
E
Rhesus Macaque
Macaca mulatta
XP_001109063
219
24908
Y100
R
A
E
V
K
G
V
Y
Q
F
C
F
S
N
E
Dog
Lupus familis
XP_858610
226
25282
Y108
T
A
S
K
N
G
T
Y
K
F
C
F
S
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q78IS1
221
25446
Y102
K
T
E
A
K
G
V
Y
R
F
C
F
S
N
E
Rat
Rattus norvegicus
Q6AY25
221
25492
Y102
K
T
E
V
K
G
V
Y
R
F
C
F
S
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518452
332
37400
Y214
T
A
S
R
N
G
T
Y
K
F
C
F
S
N
E
Chicken
Gallus gallus
XP_413948
205
23206
Y93
H
T
E
L
T
G
I
Y
T
F
C
F
S
N
E
Frog
Xenopus laevis
NP_001087434
219
25215
Y101
T
A
T
R
N
G
T
Y
K
F
C
F
S
N
E
Zebra Danio
Brachydanio rerio
NP_998077
217
24536
Y99
S
A
A
R
N
G
T
Y
K
F
C
F
S
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17528
203
22968
Y88
A
A
H
M
D
G
V
Y
T
Y
C
F
G
N
K
Sea Urchin
Strong. purpuratus
XP_788345
211
23824
I94
T
T
D
Q
A
G
T
I
E
F
C
F
S
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39704
215
24045
Y102
K
S
F
G
V
G
K
Y
T
F
C
F
S
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.3
64.1
N.A.
88.6
91.4
N.A.
42.4
68.6
62
62.2
N.A.
N.A.
N.A.
27.1
52.5
Protein Similarity:
100
99
96.8
77.8
N.A.
92.3
95
N.A.
51.8
77.8
75.8
80.6
N.A.
N.A.
N.A.
45.1
69.5
P-Site Identity:
100
100
100
60
N.A.
73.3
80
N.A.
60
60
60
60
N.A.
N.A.
N.A.
46.6
46.6
P-Site Similarity:
100
100
100
66.6
N.A.
86.6
93.3
N.A.
66.6
73.3
66.6
66.6
N.A.
N.A.
N.A.
66.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
49.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
62
8
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
47
0
0
0
0
0
8
0
0
0
0
0
85
% E
% Phe:
0
0
8
0
0
0
0
0
0
93
0
100
0
0
0
% F
% Gly:
0
0
0
8
0
100
0
0
0
0
0
0
8
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% I
% Lys:
24
0
0
8
39
0
8
0
31
0
0
0
0
0
8
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
31
0
0
0
0
0
0
0
0
100
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
24
0
0
0
0
0
0
% Q
% Arg:
24
0
0
24
0
0
0
0
16
0
0
0
0
0
0
% R
% Ser:
8
8
16
0
0
0
0
0
0
0
0
0
93
0
0
% S
% Thr:
31
31
8
0
8
0
39
0
24
0
0
0
0
0
0
% T
% Val:
0
0
0
31
8
0
47
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _