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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIP1
All Species:
34.24
Human Site:
S589
Identified Species:
75.33
UniProt:
Q9Y3R0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R0
NP_066973
1128
122423
S589
V
E
L
G
I
T
I
S
S
P
S
S
R
K
P
Chimpanzee
Pan troglodytes
XP_509203
1128
122383
S589
V
E
L
G
I
T
I
S
S
P
S
S
R
K
P
Rhesus Macaque
Macaca mulatta
XP_001117109
1128
122337
S589
V
E
L
G
I
T
I
S
S
P
S
S
R
K
P
Dog
Lupus familis
XP_531664
1122
121254
S583
V
E
L
G
I
T
I
S
S
P
S
S
R
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q925T6
1127
122039
S588
V
E
L
G
I
T
I
S
S
P
S
S
R
K
P
Rat
Rattus norvegicus
P97879
1112
120279
S588
V
E
L
G
I
T
I
S
S
P
S
S
R
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521279
546
59112
T26
G
L
T
I
S
G
G
T
D
K
D
G
K
P
R
Chicken
Gallus gallus
XP_425437
1139
124557
S614
V
E
L
G
I
T
I
S
S
P
S
S
R
K
P
Frog
Xenopus laevis
A8E0R9
1083
118442
P563
D
V
A
E
S
V
V
P
S
S
G
T
F
H
V
Zebra Danio
Brachydanio rerio
NP_001038316
1143
124419
S609
V
E
L
G
I
T
I
S
S
P
S
S
R
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790732
1120
120152
S576
L
G
D
G
L
L
I
S
T
V
K
K
G
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
94.9
N.A.
95.7
94.1
N.A.
33
85.7
60.3
75.2
N.A.
N.A.
N.A.
N.A.
43
Protein Similarity:
100
99.7
99.5
96.4
N.A.
97.3
96
N.A.
40.3
91.5
74.8
84.7
N.A.
N.A.
N.A.
N.A.
60.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
6.6
100
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
20
100
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% D
% Glu:
0
73
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
10
0
82
0
10
10
0
0
0
10
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
10
73
0
82
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
10
10
73
0
% K
% Leu:
10
10
73
0
10
10
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
73
0
0
0
10
73
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
10
% R
% Ser:
0
0
0
0
19
0
0
82
82
10
73
73
0
10
0
% S
% Thr:
0
0
10
0
0
73
0
10
10
0
0
10
0
0
0
% T
% Val:
73
10
0
0
0
10
10
0
0
10
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _