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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 22.12
Human Site: S1266 Identified Species: 37.44
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S1266 I E A V S R T S M D T S S T A
Chimpanzee Pan troglodytes XP_531552 2298 258112 S1266 I E A V S R T S M D T S S T A
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S1254 I E A V S R T S M D T S S T A
Dog Lupus familis XP_544874 2297 257913 S1266 I E A V S R T S M D T S S T A
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 G1264 I E A V S R T G I D T S S T A
Rat Rattus norvegicus XP_001055500 2294 257490 G1263 I E A V S R T G I D T S S T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 G1251 L A G Q S F Y G Q L P A H S P
Chicken Gallus gallus XP_001232723 2283 257889 S1248 V E A V A S T S M D T S S T A
Frog Xenopus laevis Q642P2 2270 256829 S1240 I E S V A A T S M D T S S T A
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 F1556 C L S I T T S F S S A S L K Q
Honey Bee Apis mellifera XP_395999 2434 273219 V1411 C C A A T T S V T N T T K N T
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 C1329 D L T S L W K C K I S A L E F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 V719 P R H Q I L G V K N L K T L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 6.6 80 80 0 N.A. 6.6 13.3 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 26.6 93.3 93.3 0 N.A. 33.3 40 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 58 8 15 8 0 0 0 0 8 15 0 0 58 % A
% Cys: 15 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 58 0 0 0 0 0 % D
% Glu: 0 58 0 0 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 8 % F
% Gly: 0 0 8 0 0 0 8 22 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 50 0 0 8 8 0 0 0 15 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 15 0 0 8 8 8 0 % K
% Leu: 8 15 0 0 8 8 0 0 0 8 8 0 15 8 0 % L
% Met: 0 0 0 0 0 0 0 0 43 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 15 0 0 0 8 8 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % P
% Gln: 0 0 0 15 0 0 0 0 8 0 0 0 0 0 8 % Q
% Arg: 0 8 0 0 0 43 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 15 8 50 8 15 43 8 8 8 65 58 8 0 % S
% Thr: 0 0 8 0 15 15 58 0 8 0 65 8 8 58 8 % T
% Val: 8 0 0 58 0 0 0 15 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _