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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 36.06
Human Site: S2021 Identified Species: 61.03
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S2021 S S S L K L F S S F E Q K A M
Chimpanzee Pan troglodytes XP_531552 2298 258112 S2021 S S S L K L F S S F E Q K A M
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S2009 S S S L K L F S S F E Q K A M
Dog Lupus familis XP_544874 2297 257913 S2022 S S S L K L F S S F E Q K A M
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 S2019 S S S L K L F S S F E Q K A M
Rat Rattus norvegicus XP_001055500 2294 257490 S2018 S S S L K L F S S F E Q K A M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 S1974 S S S L K L F S S Y E Q K A M
Chicken Gallus gallus XP_001232723 2283 257889 P2007 S S A L K L Y P S F E Q K A M
Frog Xenopus laevis Q642P2 2270 256829 S1994 S S S L K L Y S S S E Q K A M
Zebra Danio Brachydanio rerio NP_956904 817 86774 T546 D Q L V S G S T P Y V A V S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 T2310 A G S L N I F T S R D Q E Y E
Honey Bee Apis mellifera XP_395999 2434 273219 M2162 D L M N R V S M A Q S S S I S
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 A2096 L A S S Q L L A S M S S Y S Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 G1427 D K K L S V I G S D Q T W E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 80 86.6 0 N.A. 33.3 0 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 93.3 33.3 N.A. 66.6 20 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 0 0 8 8 0 0 8 0 65 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 22 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 65 0 8 8 8 % E
% Phe: 0 0 0 0 0 0 58 0 0 50 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 0 0 0 8 0 % I
% Lys: 0 8 8 0 65 0 0 0 0 0 0 0 65 0 8 % K
% Leu: 8 8 8 79 0 72 8 0 0 0 0 0 0 0 8 % L
% Met: 0 0 8 0 0 0 0 8 0 8 0 0 0 0 65 % M
% Asn: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 8 0 0 0 0 8 8 72 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 65 65 72 8 15 0 15 58 86 8 15 15 8 15 8 % S
% Thr: 0 0 0 0 0 0 0 15 0 0 0 8 0 0 0 % T
% Val: 0 0 0 8 0 15 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 15 0 0 15 0 0 8 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _