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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 46.06
Human Site: S50 Identified Species: 77.95
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S50 K L N K A L Q S N L R Y S L L
Chimpanzee Pan troglodytes XP_531552 2298 258112 S50 K L N K A L Q S N L R Y S L L
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S50 K L N K A L Q S N L R Y S L L
Dog Lupus familis XP_544874 2297 257913 S50 K L N K A L Q S N L R Y S L L
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 S50 K L N K A L Q S N L K Y S L L
Rat Rattus norvegicus XP_001055500 2294 257490 S50 K L N K A L Q S N L K Y S L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 S50 K L S K A L Q S N L K Y S L L
Chicken Gallus gallus XP_001232723 2283 257889 S50 K L N K A L Q S N L K Y S L L
Frog Xenopus laevis Q642P2 2270 256829 T50 K L N K A L Q T N L K Y C L L
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 S55 K L S K A I S S N T Q Y Q V I
Honey Bee Apis mellifera XP_395999 2434 273219 S53 K L N K V L L S H M K F P V I
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 S55 K L A K V F Q S N A K F C A I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 93.3 80 0 N.A. 46.6 40 40 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 93.3 0 N.A. 80 80 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 72 0 0 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 15 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 22 % I
% Lys: 86 0 0 86 0 0 0 0 0 0 50 0 0 0 0 % K
% Leu: 0 86 0 0 0 72 8 0 0 65 0 0 0 65 65 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 65 0 0 0 0 0 79 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 72 0 0 0 8 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 29 0 0 0 0 % R
% Ser: 0 0 15 0 0 0 8 79 0 0 0 0 58 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % T
% Val: 0 0 0 0 15 0 0 0 0 0 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 72 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _