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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 10.61
Human Site: S656 Identified Species: 17.95
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S656 A S G E E S K S E E P A G K R
Chimpanzee Pan troglodytes XP_531552 2298 258112 S656 A S G E E S K S E E P A G K R
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S644 A S G E E S K S E E P A G K R
Dog Lupus familis XP_544874 2297 257913 H656 T S G E E D K H E E P A G Q R
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 P656 V S G E E N K P E E P P G K G
Rat Rattus norvegicus XP_001055500 2294 257490 P655 V S G E E S K P E G A P G K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 A656 G D E T P S A A T P G Q R G K
Chicken Gallus gallus XP_001232723 2283 257889 S654 E A N N E S I S A I N L S G K
Frog Xenopus laevis Q642P2 2270 256829 N652 Q L K G E G Q N S P E N G V M
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 G679 T S A E V S D G P S A E E P K
Honey Bee Apis mellifera XP_395999 2434 273219 N643 K T G Y I E T N T I N S P T K
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 V733 E L L C K I Y V K S V Q V L E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 N143 H L I E L Y D N Y I L L L P Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 100 73.3 N.A. 66.6 60 N.A. 6.6 20 13.3 0 N.A. 20 6.6 0 N.A.
P-Site Similarity: 100 100 100 80 N.A. 73.3 60 N.A. 20 33.3 26.6 0 N.A. 26.6 33.3 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 8 8 0 0 0 8 8 8 0 15 29 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 15 0 0 0 0 0 0 0 0 % D
% Glu: 15 0 8 58 58 8 0 0 43 36 8 8 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 50 8 0 8 0 8 0 8 8 0 50 15 8 % G
% His: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 8 8 0 0 22 0 0 0 0 0 % I
% Lys: 8 0 8 0 8 0 43 0 8 0 0 0 0 36 29 % K
% Leu: 0 22 8 0 8 0 0 0 0 0 8 15 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 8 8 0 8 0 22 0 0 15 8 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 15 8 15 36 15 8 15 0 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 0 15 0 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 29 % R
% Ser: 0 50 0 0 0 50 0 29 8 15 0 8 8 0 8 % S
% Thr: 15 8 0 8 0 0 8 0 15 0 0 0 0 8 0 % T
% Val: 15 0 0 0 8 0 0 8 0 0 8 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 8 8 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _