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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOPEY2 All Species: 12.73
Human Site: S716 Identified Species: 21.54
UniProt: Q9Y3R5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y3R5 NP_005119.2 2298 258184 S716 T K S S E S P S S S P S S P A
Chimpanzee Pan troglodytes XP_531552 2298 258112 S716 T K S S E S P S S S P S S P A
Rhesus Macaque Macaca mulatta XP_001084653 2286 256620 S704 T K N S E S P S S S P S S P A
Dog Lupus familis XP_544874 2297 257913 S716 T K S A E L P S P L P R S P G
Cat Felis silvestris
Mouse Mus musculus Q3UHQ6 2295 257491 V716 S S E S L S S V P S S P Y R K
Rat Rattus norvegicus XP_001055500 2294 257490 A715 S S E S L S S A P S S P H R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512569 2247 251024 P716 K S S E P A F P S G L R N D K
Chicken Gallus gallus XP_001232723 2283 257889 C714 S S N L S S D C N S D N K K E
Frog Xenopus laevis Q642P2 2270 256829 E712 P N K T T N K E T E E E W D I
Zebra Danio Brachydanio rerio NP_956904 817 86774
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZBE8 2599 291169 P739 L L H I E S E P K E C S V K V
Honey Bee Apis mellifera XP_395999 2434 273219 D703 F Y V K F V S D R V L T K E R
Nematode Worm Caenorhab. elegans Q9XW10 2417 267134 S793 A V W L G I G S R K F C T E Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03921 1698 194669 V203 F W Q T L F L V M T A N K G R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 94.8 89.9 N.A. 86.4 86.4 N.A. 73.9 75.2 69 21.9 N.A. 27.6 32.1 22.3 N.A.
Protein Similarity: 100 99.7 96 94.6 N.A. 92.4 92.5 N.A. 83 85.4 82 28.7 N.A. 47 53.2 40.9 N.A.
P-Site Identity: 100 100 93.3 60 N.A. 20 20 N.A. 13.3 13.3 0 0 N.A. 20 0 6.6 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 26.6 33.3 N.A. 26.6 40 20 0 N.A. 20 6.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 8 0 8 0 0 8 0 0 0 22 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 8 0 0 8 0 0 15 0 % D
% Glu: 0 0 15 8 36 0 8 8 0 15 8 8 0 15 8 % E
% Phe: 15 0 0 0 8 8 8 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 8 0 0 8 0 0 0 8 8 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 8 % I
% Lys: 8 29 8 8 0 0 8 0 8 8 0 0 22 15 22 % K
% Leu: 8 8 0 15 22 8 8 0 0 8 15 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 15 0 0 8 0 0 8 0 0 15 8 0 0 % N
% Pro: 8 0 0 0 8 0 29 15 22 0 29 15 0 29 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 15 0 0 15 0 15 15 % R
% Ser: 22 29 29 36 8 50 22 36 29 43 15 29 29 0 0 % S
% Thr: 29 0 0 15 8 0 0 0 8 8 0 8 8 0 0 % T
% Val: 0 8 8 0 0 8 0 15 0 8 0 0 8 0 8 % V
% Trp: 0 8 8 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _