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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY2
All Species:
20
Human Site:
T2275
Identified Species:
33.85
UniProt:
Q9Y3R5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R5
NP_005119.2
2298
258184
T2275
P
F
L
D
F
P
V
T
D
S
P
R
I
L
K
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
T2275
P
F
L
D
F
P
V
T
D
S
P
R
I
L
K
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
T2263
P
F
L
D
F
P
V
T
D
S
S
R
V
L
K
Dog
Lupus familis
XP_544874
2297
257913
T2274
P
A
L
E
F
P
V
T
D
S
P
R
V
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHQ6
2295
257491
T2272
A
A
P
E
C
P
V
T
E
N
P
R
V
L
R
Rat
Rattus norvegicus
XP_001055500
2294
257490
A2271
T
V
P
E
F
P
V
A
D
S
L
R
V
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512569
2247
251024
G2224
L
F
M
D
Y
S
A
G
D
G
S
R
I
L
K
Chicken
Gallus gallus
XP_001232723
2283
257889
Y2257
S
A
S
L
S
V
D
Y
V
G
G
N
S
M
K
Frog
Xenopus laevis
Q642P2
2270
256829
V2246
E
P
T
I
E
Y
P
V
E
D
F
T
K
V
L
Zebra Danio
Brachydanio rerio
NP_956904
817
86774
L795
G
S
S
V
L
Q
T
L
T
G
D
I
S
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
T2569
Q
P
R
N
F
A
D
T
E
N
D
V
A
N
C
Honey Bee
Apis mellifera
XP_395999
2434
273219
S2412
R
S
S
D
T
Q
A
S
L
N
I
T
Q
V
E
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
F2367
F
E
E
L
R
P
F
F
Y
T
L
A
N
L
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03921
1698
194669
K1676
L
S
Y
L
H
Y
E
K
V
Y
G
L
G
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
89.9
N.A.
86.4
86.4
N.A.
73.9
75.2
69
21.9
N.A.
27.6
32.1
22.3
N.A.
Protein Similarity:
100
99.7
96
94.6
N.A.
92.4
92.5
N.A.
83
85.4
82
28.7
N.A.
47
53.2
40.9
N.A.
P-Site Identity:
100
100
86.6
73.3
N.A.
40
46.6
N.A.
46.6
6.6
0
0
N.A.
13.3
6.6
13.3
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
73.3
66.6
N.A.
60
13.3
13.3
0
N.A.
33.3
33.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
0
0
0
8
15
8
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
36
0
0
15
0
43
8
15
0
0
0
0
% D
% Glu:
8
8
8
22
8
0
8
0
22
0
0
0
0
0
8
% E
% Phe:
8
29
0
0
43
0
8
8
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
8
0
22
15
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
8
8
22
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
36
% K
% Leu:
15
0
29
22
8
0
0
8
8
0
15
8
0
58
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
22
0
8
8
15
8
% N
% Pro:
29
15
15
0
0
50
8
0
0
0
29
0
0
0
8
% P
% Gln:
8
0
0
0
0
15
0
0
0
0
0
0
8
0
15
% Q
% Arg:
8
0
8
0
8
0
0
0
0
0
0
50
0
0
8
% R
% Ser:
8
22
22
0
8
8
0
8
0
36
15
0
15
8
0
% S
% Thr:
8
0
8
0
8
0
8
43
8
8
0
15
0
0
0
% T
% Val:
0
8
0
8
0
8
43
8
15
0
0
8
29
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
15
0
8
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _