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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY2
All Species:
36.36
Human Site:
Y494
Identified Species:
61.54
UniProt:
Q9Y3R5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R5
NP_005119.2
2298
258184
Y494
D
V
I
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
Y494
D
V
I
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
Y482
D
V
I
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Dog
Lupus familis
XP_544874
2297
257913
Y494
D
V
I
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHQ6
2295
257491
Y494
D
V
I
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Rat
Rattus norvegicus
XP_001055500
2294
257490
Y494
D
V
I
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512569
2247
251024
Y494
D
V
L
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Chicken
Gallus gallus
XP_001232723
2283
257889
Y492
D
V
I
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Frog
Xenopus laevis
Q642P2
2270
256829
Y494
D
V
I
P
L
E
L
Y
S
E
V
Q
T
Q
Y
Zebra Danio
Brachydanio rerio
NP_956904
817
86774
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
C510
I
T
A
S
L
K
L
C
M
K
I
V
S
R
V
Honey Bee
Apis mellifera
XP_395999
2434
273219
F482
S
E
H
L
P
G
L
F
H
E
I
I
S
K
L
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
D542
E
M
C
N
V
E
S
D
P
T
I
R
T
Q
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03921
1698
194669
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
89.9
N.A.
86.4
86.4
N.A.
73.9
75.2
69
21.9
N.A.
27.6
32.1
22.3
N.A.
Protein Similarity:
100
99.7
96
94.6
N.A.
92.4
92.5
N.A.
83
85.4
82
28.7
N.A.
47
53.2
40.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
100
0
N.A.
13.3
13.3
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
0
N.A.
46.6
40
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
65
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
72
0
0
0
72
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
8
% H
% Ile:
8
0
58
0
0
0
0
0
0
0
22
8
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% K
% Leu:
0
0
8
8
72
0
79
0
0
0
0
0
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
65
8
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
65
0
72
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% R
% Ser:
8
0
0
8
0
0
8
0
65
0
0
0
15
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
0
72
0
0
% T
% Val:
0
65
0
0
8
0
0
0
0
0
65
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
65
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _